Results 51 to 60 of about 336,694 (310)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

DNA methylation is maintained with high fidelity in the honey bee germline and exhibits global non-functional fluctuations during somatic development

Epigenetics & Chromatin, 2019
Background DNA methylation of active genes, also known as gene body methylation, is found in many animal and plant genomes. Despite this, the transcriptional and developmental role of such methylation remains poorly understood.
Keith D. Harris, James P. B. Lloyd, Katherine Domb, Daniel Zilberman, Assaf Zemach   +4 more
doaj   +1 more source

Characteristics of plant circular RNAs

Briefings in Bioinformatics, 2018
Circular RNA (circRNA) is a kind of covalently closed single-stranded RNA molecules that have been proved to play important roles in transcriptional regulation of genes in diverse species. With the rapid development of bioinformatics tools, a huge number (95143) of circRNAs have been identified from different plant species, providing an opportunity for
Qinjie Chu, Panpan Bai, Xintian Zhu, Xingchen Zhang, Lingfeng Mao 0002, Qian-Hao Zhu, Longjiang Fan, Chu-Yu Ye   +7 more
openaire   +2 more sources

RNA silencing movement in plants [PDF]

Journal of Integrative Plant Biology, 2015
AbstractMulticellular organisms, like higher plants, need to coordinate their growth and development and to cope with environmental cues. To achieve this, various signal molecules are transported between neighboring cells and distant organs to control the fate of the recipient cells and organs.
Glykeria, Mermigka, Frédéric, Verret, Kriton, Kalantidis   +2 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Synthesis of complementary RNA by RNA-dependent RNA polymerases in plant extracts is independent of an RNA primer

, 2008
RNA-dependent RNA polymerase (RDR) activities were readily detected in extracts from cauliflower and broccoli florets, Arabidopsis thaliana (L.) Heynh callus tissue and broccoli nuclei.
Waterhouse, Peter M., Zhang, Lan, Waterhouse, PM, Dennis, ES, Unrau, PJ, Dennis, Elisabeth S., Unrau, Peter J., Wang, L, Smith, NA, Wang, Ming-Bo, Zhang, L, Wang, Lei, Wang, MB, Smith, Neil A.   +13 more
core   +1 more source

Advances in plant gene-targeted and functional markers: a review [PDF]

, 2013
Public genomic databases have provided new directions for molecular marker development and initiated a shift in the types of PCR-based techniques commonly used in plant science.
Ildikó Varga, Poczai, Péter, Neil Bell, Hyvönen Jaakko, Valkonen, Jari PT, Maarja Laos, Hyvönen, Jaakko, Cseh, András, Varga Ildikó, Varga, Ildikó, Laos, Maarja, Cseh András, Bell Neil, Poczai Péter, Valkonen, Jari, Cseh, András Attila, Péter Poczai, Jari PT Valkonen, Valkonen Jari PT, Jaakko Hyvönen, Bell, Neil, András Cseh, Laos Maarja   +22 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

RNA silencing in plants: Yesterday, today, and tomorrow [PDF]

, 2008
RNA silencing has become a major focus of molecular biology and biomedical research around the world. This is highlighted by a simple PubMed search for “RNA silencing,” which retrieves almost 9,000 articles.
Wang, M.B., Eamens, A., Smith, N.A., Waterhouse, P.M.   +3 more
core   +1 more source