Results 101 to 110 of about 193,455 (318)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Genome sequence of Ensifer arboris strain LMG 14919T: a microsymbiont of the legume Prosopis chilensis growing in Kosti, Sudan [PDF]

, 2014
Ensifer arboris LMG 14919T is an aerobic, motile, Gram-negative, non-spore-forming rod that can exist as a soil saprophyte or as a legume microsymbiont of several species of legume trees.
Bräu, Lambert, Detter, Chris, Goodwin, Lynne, Han, Cliff, Huntemann, Marcel, Ivanova, Natalia, Kyrpides, Nikos, Liolios, Konstantinos, Markowitz, Victor, Mavrommatis, Konstantinos, Munk, Christine, Pati, Amrita, Reeve, Wayne Gerald, Tapia, Roxanne, Tian, Rui, Willems, Anne, Woyke, Tanja   +16 more
core   +1 more source

Optimal Eukaryotic 18S and Universal 16S/18S Ribosomal RNA Primers and Their Application in a Study of Symbiosis

PLoS ONE, 2014
Eukaryotic 18S ribosomal RNA (rRNA) gene primers that feature a wide coverage are critical in detecting the composition of eukaryotic microscopic organisms in ecosystems.
Yong Wang, R. Tian, Zhao-Ming Gao, S. Bougouffa, P. Qian   +4 more
semanticscholar   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Dynamic microsatellites in transcribed regions of gastropod mitochondrial 16S rDNA [PDF]

, 2006
Length variations of repetitive sequences in different AT-rich loop-coding regions of mitochondrial 16S rDNA in two gastropod species were discovered during intraspecific haplotype surveys. Examination of the discrete length variation of the basic repeat
Bugert, Monika, Pfenninger, Markus
core  

Complete genome sequence of Planctomyces limnophilus type strain (Mü 290). [PDF]

, 2010
Planctomyces limnophilus Hirsch and Müller 1986 belongs to the order Planctomycetales, which differs from other bacterial taxa by several distinctive features such as internal cell compartmentalization, multiplication by forming buds directly from the ...
Bristow, James, Chang, Yun-Juan, Chen, Amy, Cheng, Jan-Fang, Eisen, Jonathan A, Glavina Del Rio, Tijana, Goodwin, Lynne, Göker, Markus, Hauser, Loren, Hugenholtz, Philip, Ivanova, Natalia, Jeffries, Cynthia D, Klenk, Hans-Peter, Kyrpides, Nikos C, Labutti, Kurt, Land, Miriam, Lapidus, Alla, Liolios, Konstantinos, Lucas, Susan, Markowitz, Victor, Mavromatis, Konstantinos, Mikhailova, Natalia, Nolan, Matt, Palaniappan, Krishna, Pati, Amrita, Pitluck, Sam, Rohde, Manfred, Schneider, Susanne, Sikorski, Johannes, Tice, Hope, Tindall, Brian J, Woyke, Tanja   +31 more
core   +1 more source

Structural basis for ribosomal 16S rRNA cleavage by the cytotoxic domain of colicin E3

Nature Structural &Molecular Biology, 2010
The toxin colicin E3 targets the 30S subunit of bacterial ribosomes and cleaves a phosphodiester bond in the decoding center. We present the crystal structure of the 70S ribosome in complex with the cytotoxic domain of colicin E3 (E3-rRNase).
C. Ng, Kathrin Lang, Nicola A. G. Meenan, Amit Sharma, A. Kelley, C. Kleanthous, V. Ramakrishnan   +6 more
semanticscholar   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Estuarine Nitrifiers: New Players, Patterns and Processes [PDF]

, 2010
Ever since the first descriptions of ammonia-oxidizing Bacteria by Winogradsky in the late 1800s, the metabolic capability of aerobic ammonia oxidation has been restricted to a phylogenetically narrow group of bacteria.
Bernhard, Anne E, Bollmann, Annette
core   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source