Results 171 to 180 of about 994,915 (210)
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Secondary Structure of 16 S Ribosomal RNA
Science, 1981A secondary structure model for 16 S ribosomal RNA which is based on available chemical, enzymatic, and comparative sequence data shows good agreement between constraints dictated by the model and a wide variety of experimental observations.
H F, Noller, C R, Woese
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Scanning tunnelling microscopy of 16S ribosomal RNA in water
Biochemical and Biophysical Research Communications, 1991The scanning tunnelling microscope has been used to image 16S ribosomal RNA molecules in water electrophoretically deposited on graphite surface. Two kinds of images have been obtained: images showing aggregates of 16S ribosomal RNA molecules similar to those obtained from DNA solutions and others showing individual 16S ribosomal RNA molecules.
E, Lesniewska +4 more
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Methylation of 16S RNA during ribosome assembly in vitro
Nature, 1974Methyl deficient 16S RNA from kasugamycin resistant Escherichia coli has been used to study methylation of RNA during ribosome assembly in vitro. Methylation occurs at an intermediate stage and is inhibited at a late stage of assembly. 30S ribosomal proteins required for methylation, and inhibition, have been identified.
P, Thammana, W A, Held
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Interaction of antibiotics with functional sites in 16S ribosomal RNA
Nature, 1987Chemical footprinting shows that several classes of antibiotics (streptomycin, tetracycline, spectinomycin, edeine, hygromycin and the neomycins) protect concise sets of highly conserved nucleotides in 16S ribosomal RNA when bound to ribosomes. These findings have strong implications for the mechanism of action of these antibiotics and for the ...
D, Moazed, H F, Noller
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To Knot or Not to Knot? Examination of 16S Ribosomal RNA Models
Journal of Biomolecular Structure and Dynamics, 1998The presence of topological knots in large RNA structures is highly unlikely given that 1) no RNA structures determined thus far contain topological knots, 2) secondary structure maps for most RNA molecules are knot free, 3) there are no known RNA topoisomerases, and 4) it is difficult to imagine how knots could be formed specifically and uniquely ...
M S, VanLoock, B A, Harris, S C, Harvey
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Complementary binding of oligonucleotides with 16S RNA and ribosomal ribonucleoproteins
Molecular Biology Reports, 1975The accessibility of single-stranded sequences in 16S RNA in free state and in ribonucleoprotein particles (RNP) to complementary binding with isoplith fractions of oligonucleotides was studied. RNP had different protein composition and corresponded to intermediate stages of E. coli 30S subunit assembly in vitro.
A M, Kopylov +3 more
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Images of 16S ribosomal RNA by scanning tunnelling microscopy
Journal of Microscopy, 1991SUMMARYWe report the use of scanning tunnelling microscopy (STM) to study surface topographies of complex nucleic acid structures. From low‐resolution STM images of uncoated 16S ribosomal RNA, we demonstrate the possibility of determining several objective parameters (molecular mass and radius of gyration) in order to characterize and identify the ...
P J, Flamion +5 more
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16S Mitochondrial Ribosomal RNA Degradation Is Associated with Apoptosis
Free Radical Biology and Medicine, 1997The use of mitochondrial RNA as an indicator of apoptosis was investigated. Exposure of HA-1 fibroblastic cells to 10 micromol H(2)O(2) per 10(7) cells induced nuclear fragmentation, cell shrinkage, and internucleosomal DNA fragmentation, all characteristics of apoptosis.
D R, Crawford +5 more
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Chromosomal loci for 16S ribosomal RNA in Escherichia coli
Molecular and General Genetics MGG, 1972Genetic loci for 16S ribosomal RNA (rRNA) on the Escherichia coli chromosome were determined using the K-sequence, a characteristic oligonucleotide of strain K12, as a genetic marker. Oligonucleotide analyses of 16S rRNA from various recombinants between strain K12 and strain B(H) showed that the loci for 16S rRNA containing the K-sequence were near ...
M, Matsubara, R, Takata, S, Osawa
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Biochemistry, 1989
16S ribosomal RNA was made by in vitro transcription of a cloned gene, and its structure was compared to authentic 16S ribosomal RNA. The comparison was made by subjecting the two types of 16S rRNA to chemical reagents that react specifically with unpaired bases and determining the extent of reaction by reverse transcription and gel electrophoresis of ...
G, Ericson, K, Chevli, P, Wollenzien
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16S ribosomal RNA was made by in vitro transcription of a cloned gene, and its structure was compared to authentic 16S ribosomal RNA. The comparison was made by subjecting the two types of 16S rRNA to chemical reagents that react specifically with unpaired bases and determining the extent of reaction by reverse transcription and gel electrophoresis of ...
G, Ericson, K, Chevli, P, Wollenzien
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