Results 71 to 80 of about 203,757 (346)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

16S Ribosomal RNA-Based Analysis of Thermophilic Bacteria in Gedongsongo Hot Spring

Microbiology Indonesia, 2010
Denaturing gradient gel electrophoresis was used to identify the bacterial community at the Gedongsongo (WGS-2) hot spring. The bacterial samples were obtained from both culture dependent and independent strategies.
AGUSTINA LULUSTYANINGATI NURUL AMININ1, FIDA MADAYANTI, PINGKAN ADITIAWATI, . AKHMALOKA   +3 more
doaj   +1 more source

Molecular biological methods for studying the gut microbiota : the EU human gut flora project [PDF]

Seven European laboratories co-operated in a joint project (FAIR CT97-3035) to develop, refine and apply molecular methods towards facilitating elucidation of the complex composition of the human intestinal microflora and to devise robust methodologies ...
Blaut, M., Collins, M.D., Dore, J., Loo, J., van, Vos, W.M., de, Welling, G.W.   +5 more
core   +2 more sources

Anoxic nitrification in marine sediments [PDF]

, 2004
Nitrate peaks are found in pore-water profiles in marine sediments at depths considerably below the conventional zone of oxic nitrification. These have been interpreted to represent nonsteady- state effects produced by the activity of nitrifying ...
Anschutz, P., Barnes, J., Davies, I.M., Freitag, T.E., Harris, S.J., Hayes, P.J., Krom, M.D., Mortimer, R.J.G., Prosser, J.I.   +8 more
core   +1 more source

Reading canonical and modified nucleotides in 16S ribosomal RNA using nanopore direct RNA sequencing

bioRxiv, 2017
The ribosome small subunit is expressed in all living cells. It performs numerous essential functions during translation, including formation of the initiation complex and proofreading of base-pairs between mRNA codons and tRNA anticodons.
Andrew M. Smith, Miten Jain, Logan Mulroney, Daniel R. Garalde, M. Akeson   +4 more
semanticscholar   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

The complete mitochondrial genome of Glossaulax reiniana (Littorinimorpha: Naticidae)

Mitochondrial DNA. Part B. Resources, 2018
In the present study, the complete mitochondrial genome of Glossaulax reiniana was determined using the next-generation sequencing. The circular genome was found to be 15,254 bp in length and had an overall nucleotide composition of 30.6% A, 14.1% C, 15 ...
Peng-Yu Li, Yi Yang, Yong-Guo Li, Shao-E Sun   +3 more
doaj   +1 more source

Frequency of Bacetrial Content Finding in Persistant Periapical Lesions

Acta Stomatologica Croatica, 2017
Objectives: To determine the percentage of persistant apical lesions positive for bacterial nucleic acids, to detect microorganisms difficult to cultivate in persistant apical lesions by PCR and relate them to endodontic failure, clinical symptoms and ...
Joško Grgurević, Ana Ivanišević Malčić, Arjana Tambić Andrašević, Goranka Prpić Mehičić, Sania Kuzmac, Silvana Jukić   +5 more
doaj   +1 more source

Highly efficient RNA-synthesizing system that uses isolated human mitochondria: new initiation events and in vivo-like processing patterns [PDF]

, 1984
A highly efficient RNA-synthesizing system with isolated HeLa cell mitochondria has been developed and characterized regarding its requirements and its products.
Attardi, Giuseppe, Gaines, George
core  

Analysis of endometrial microbiota by 16S ribosomal RNA gene sequencing among infertile patients: a single‐center pilot study

Reproductive Medicine and Biology, 2018
The present study aimed to analyze the endometrial and vaginal microbiome among a Japanese infertile population by sequencing and the impact of the endometrial and vaginal environment on implantation.
K. Kyono, T. Hashimoto, Y. Nagai, Y. Sakuraba   +3 more
semanticscholar   +1 more source