Results 61 to 70 of about 1,272,206 (308)

Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan [PDF]

, 2015
Several pathways modulating longevity and stress resistance converge on translation by targeting ribosomal proteins or initiation factors, but whether this involves modifications of ribosomal RNA is unclear.
Wilson, Iain B H, Mohr, Thomas, Mattanovich, Diethard, Breitenbach, Michael, Linder, Angela, Karl, Thomas, Amring, Manuela, Wilson, Iain B.H., Grillari-Voglauer, Regina, Polacek, Norbert, Angerer, Tina B., Rinnerthaler, Mark, Angerer, Tina B, Pircher, Andreas, Schosserer, Markus, Grillari, Johannes, Sharma, Sunny, Minois, Nadege, Breitenbach-Koller, Hannelore, Entian, Karl-Dieter, Kriegner, Albert, Steiger, Matthias, Breitenbach-Koller, Lore, Pfeifenberger, Sigrid, Dellago, Hanna, Calle-Perez, Alfonso, Brandl, Clemens, Weinhäusel, Andreas, Harreither, Eva, Kos, Martin, Sonntagbauer, Markus, Gerstl, Matthias Peter, Calle-Perez A, Pfeifenberger S, Kos M, Linder A, Grillari-Voglauer R, Grillari, Johannes; orcid:, Steiger, Matthias; orcid:, Amring M, Breitenbach M, Brandl C, Sharma S, Steiger M, Polacek N, Harreither E, Grillari J, Pircher A, Mohr T, Breitenbach-Koller L, Kriegner A, Gerstl MP, Dellago H, Entian KD, Mattanovich D, Karl T, Weinhäusel A, Wilson IB, Rinnerthaler M, Schosserer M, Sonntagbauer M, Angerer TB, Minois N   +62 more
core   +2 more sources

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

MOLECULAR IDENTIFICATION OF SEVERAL CLINICALLYIMPORTANT BACTERIA INCLUDING ENTEROBACTERIA BYPARTIAL 16S RIBOSOMAL RNA GENE SEQUENCE COMPARISON

Zdravniški Vestnik, 2008
BACKGROUND The correct identification of bacterial isolates is paramount for the correct diagnosis andtreatment of patients. The standard approach for bacterial identification relies on phenotypic tests, which are often time-consuming and unreliable when
Janez Šimenc, Andrej Golle, Uroš Potočnik   +2 more
doaj  

KnotInFrame: prediction of –1 ribosomal frameshift events [PDF]

, 2008
Theis C, Reeder J, Giegerich R. KnotInFrame: prediction of –1 ribosomal frameshift events. Nucleic Acids Research. 2008;36(18):6013-6020.Programmed –1 ribosomal frameshift (–1 PRF) allows for alternative reading frames within one mRNA.
Corinna Theis, Theis, Corinna, Jens Reeder, Robert Giegerich, Reeder, Jens, Giegerich, Robert   +5 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

16S ribosomal RNA sequencing and molecular serotyping of Avibacterium paragallinarum isolated from Indian field conditions [PDF]

Veterinary World, 2017
Aim: This study was aimed at identifying Indian field isolates of Avibacterium paragallinarum on both molecular as well as serological levels that cause infectious coryza in chickens.
Vihang Vithalrao Patil, Debendranath Mishra, Dilip Vithalrao Mane   +2 more
doaj   +1 more source

Differential polyadenylation of ribosomal RNA during post-transcriptional processing in Leishmania. [PDF]

, 2005
The protozoan parasite Leishmania belongs to the most ancient eukaryotic lineages and this is reflected in several distinctive biological features, such as eukaryotic polycistronic transcription and RNA trans-splicing.
Laurent, T., Chappuis, F., Llanos-Cuentas, A., Llanos-Cuentas, A, V. YARDLEY, F. CHAPPUIS, Laurent, T, T. LAURENT, Dujardin, J. C., Vandesompele, J, J.-C. DUJARDIN, DE DONCKER, S, S. RIJAL, Decuypere, S., S. DECUYPERE, Yardley, V, De Donckeri, S, Vandesompele, Jo, Rijal, S., J. AREVALO, Vandesompele, J., S. DE DONCKER, J. VANDESOMPELE, Yardley, V., Chappuis, F, Arevalo, J., Arevalo, J, Rijal, S, De Doncker, S., A. LLANOS-CUENTAS, Dujardin, JC, Decuypere, S   +31 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Reconstructing phylogeny from RNA secondary structure via simulated evolution

, 2002
DNA sequences of genes encoding functional RNA molecules (e.g., ribosomal RNAs) are commonly used in phylogenetics (i.e. to infer evolutionary history).
Fischer, Will, Geard, Nicholas
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source