Results 191 to 200 of about 44,420 (259)

Sni445 recruits box C/D snoRNPs snR4 and snR45 to guide ribosomal RNA acetylation by Kre33. [PDF]

Nucleic Acids Res
Hafner J, Zierler I, Hamze H, Favre S, Thoms M, Kunowska N, Rimser S, Albert B, Caetano T, Aguirrebengoa M, Beckmann R, Stelzl U, Kressler D, Henras AK, Pertschy B.   +14 more
europepmc   +1 more source

Germline sequence variation within the ribosomal DNA is associated with human complex traits. [PDF]

Cell Genom
Rodriguez-Algarra F, Whittaker E, Cooper M, Koren S, Conte MR, Phillippy AM, Mardakheh FK, Evans DM, Rakyan VK.   +8 more
europepmc   +1 more source

Structural studies of nedicistrovirus IRES-driven, initiation factor-independent translation shed light on key steps of eukaryotic translation elongation. [PDF]

Nucleic Acids Res
De S, Altomare CG, Abaeva IS, Dadhwal P, Garg P, Acosta-Reyes F, Brown ZP, Pestova TV, Hellen CUT, Frank J.   +9 more
europepmc   +1 more source

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

International Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer, Morghan C. Lucas, Vitus Prokosch, Thomas Keßler, Thomas Risch, Andreas Laner, Jan Henkel, Anna Benet‐Pagès, Ariane Hallermayr, Verena Steinke‐Lange, Elke Holinski‐Feder, Barbara Klink   +11 more
wiley   +1 more source

A comprehensive view on r-protein binding and rRNA domain structuring during early eukaryotic ribosome formation. [PDF]

Nucleic Acids Res
Gerhalter M, Prattes M, Grundmann LE, Grishkovskaya I, Semeraro EF, Zisser G, Kotisch H, Merl-Pham J, Hauck SM, Haselbach D, Bergler H.   +10 more
europepmc   +1 more source

High Endothelial Venules in Small Cell Lung Cancer: Prognostic Subtypes and Therapeutic Implications for Immunoradiotherapy

International Journal of Cancer, EarlyView.
ABSTRACT Small cell lung cancer (SCLC) is a highly aggressive neuroendocrine malignancy with an immunosuppressive tumor microenvironment, and current immunotherapy provides limited benefit. This highlights the need to identify microenvironmental features enabling effective immune responses.
Jiatian Fang, Zilian Wang, Hui Wang, Jianxin Xue, Kai Kang   +4 more
wiley   +1 more source

Clinical Relevance of BACH1 Expression in Non–Small Cell Lung Cancer

International Journal of Cancer, EarlyView.
ABSTRACT BTB and CNC homolog 1 (BACH1) is a redox‐sensitive transcription factor implicated in tumor progression, metabolic reprogramming, and therapy resistance in several cancers. However, its prognostic significance and role in therapy resistance in non–small cell lung cancer (NSCLC) remain unclear.
Jing Liu, Marc A. Schneider, Julia Held, Sabine Wrenger, Wenzhang Si, Michael Allgaeuer, Florian Eichhorn, Sabina Janciauskiene   +7 more
wiley   +1 more source

From Bioinformatic Modeling to Clinical Observation: Potential Implications of Ribosomal RNA Folding in <i>Blastocystis</i> sp. Isolates from Symptomatic and Asymptomatic Carriers. [PDF]

Pathogens
Martínez-Hernández F, Martínez A, Zampedri C, Romero-Valdovinos M, Jiménez-Gutiérrez C, Flores-Martínez K, Trejo-Chávez A, Villalobos G, Maravilla P.   +8 more
europepmc   +1 more source

Unlocking insights: Validating a comprehensive model for predicting spontaneous preterm delivery and microbial invasion in women facing preterm labor

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Preterm labor is a multifactorial syndrome with diverse etiologies such as infection, inflammation, uteroplacental dysfunction, stress, and immune dysregulation. Identifying women at high risk remains a challenge, and multivariate prediction models have been developed to enhance risk stratification.
Ester del Barco, Nerea Maiz, Clara Franco‐Jarava, Mireia Vargas, Silvia Arévalo, María A. Sánchez‐Durán, Carlota Rodó, Manel Mendoza, Marta Dalmau, Alba Casellas, Manuel Hernández‐González, Anna Suy, María Goya   +12 more
wiley   +1 more source

Ribosome heterogeneity and specialization in musculoskeletal physiology and pathology. [PDF]

JBMR Plus
Chabronova A, van den Akker GGH, Welting TJM, Peffers MJ.   +3 more
europepmc   +1 more source