Results 201 to 210 of about 46,527 (308)

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

ITS2 and 18S rRNA gene sequence-structure phylogeny of the Haptophyta (Haptista). [PDF]

PLoS One
Ridder L, Edvardsen B, Wolf M.
europepmc   +1 more source

Vacancy defect‐induced electron homing breaks phosphodiester bonds for RNA depletion‐driven cancer therapy

BMEMat, EarlyView.
Illustration of 5% S‐vacancy Bi2S3 mediated phosphodiester bonds cleavage in RNA of hepatocellular carcinoma cells, which suppressing ERI3 expression, inhibiting cell proliferation and promoting apoptosis. Abstract Genome‐wide hypertranscription is a hallmark of malignant progression.
Chuncheng Yang, Zehao Shen, Guangming Xiang, Zhe Liu, Huaxin Liu, Jiabei Li, Ao Wang, Yelin Wu, Peiran Zhao, Xingwu Jiang, Jinghan Wang, Xiaoqing Jiang, Wenbo Bu   +12 more
wiley   +1 more source

Analytical and clinical performance of in-house and commercial real-time PCR assays for diagnosing <i>L. infantum</i> visceral leishmaniasis: a study from a hub center in Northern Italy. [PDF]

J Clin Microbiol
Gritti T, Mola B, Argnani L, Granozzi B, Bacchiega M, Melchionda F, Dondi A, Nigrisoli G, Castaldini S, Prodi L, Lazzarotto T, Denwood M, Varani S, Ortalli M.   +13 more
europepmc   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Nucleoplasmic checkpoint of the 40S ribosomal decoding center maturation.

Cell Rep
Lau B, Li Y, Zhu J, Ye X, Fischer P, Hong X, Yuan R, Beckmann R, Hurt E, Cheng J.   +9 more
europepmc   +1 more source

Regulation of Pre-rRNA Processing in Plant: Mechanisms, Plasticity, and Developmental Implications. [PDF]

Plants (Basel)
Chen N, Huang S, Mo B, Xiong W.
europepmc   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Evidence for strong purifying selection of human <i>47S</i> ribosomal RNA genes. [PDF]

Proc Natl Acad Sci U S A
Ma X, Chow F, Galbraith B, Sultanov D, Behar EK, Hochwagen A.   +5 more
europepmc   +1 more source

Single‐Cell Profiling Reveals Distinct Immune Hallmarks in Untreated Primary Colorectal and Liver Metastasis Cancers

Chronic Diseases and Translational Medicine, EarlyView.
Features the major cell type compositions among colon and liver metastasis. (A) The study design for single‐cell data analysis. (B) The annotated major cell types. Each type was labeled with a special color. (C) Dot plot of canonical marker genes for major cell types. (D) Bar plot of the percentage for each cell type in individuals. (E) Bar plot of the
Zhixun Zhao, Haipeng Chen, Xu Guan, Zheng Jiang, Zheng Liu, Ming Yang, Hengchang Liu, Tianli Chen, Shuangmei Zou, Yibo Gao, Xishan Wang   +10 more
wiley   +1 more source