Results 231 to 240 of about 77,694 (290)

Microbiota humanization drives human‐like metabolic and immune transcriptomic shifts in pigs

iMetaOmics, EarlyView.
This study successfully established gut microbiota‐humanized pigs, achieved human‐like remodeling of the serum metabolome, and uncovered transcriptional alterations in immune cell subsets. These findings advance our understanding of how human gastrointestinal microorganisms affect host metabolism and the immune function in a porcine model.
Zhaoqi Zhang, Yanan Xu, Kun Pang, Changhong Wu, Chenxu Zhao, Tong Lei, Jiayu Zhang, Tang Hai, Fangqing Zhao, Yong Zhao   +9 more
wiley   +1 more source

Phylogenetic and genetic evolutionary analyses of the mitochondrial genome of <i>Mastophorus muris</i> in <i>Neodon fuscus</i> from the Qinghai-Tibetan Plateau. [PDF]

Microbiol Spectr
Ge H, Zhang H, Meng R, Xu S, Zhao H, Lin W, Li J, Fu Y.   +7 more
europepmc   +1 more source

Spatio‐temporal characteristics of the gastrointestinal resistome in a cow‐to‐calf model and its environmental dissemination in a dairy production system

iMeta, EarlyView.
This study revealed spatio‐temporal characteristics of gastrointestinal resistome in a cow‐to‐calf model and the pattern of their spread to the environment and offspring in the dairy production system. The gastrointestinal tract of dairy cows is a natural reservoir of resistomes and distinguished by gut sites and regions.
Shuai Liu, Yimin Zhuang, Tianyu Chen, Duo Gao, Jianxin Xiao, Jinfeng Wang, Jinghui Li, Xinjie Zhao, Rong Peng, Wenli Guo, Jialin Wei, Mo Sha, Jingjun Wang, Jiaying Ma, Mei Ma, Mengmeng Li, Wei Wang, Ya‐Jing Wang, Shengli Li, Zhijun Cao   +19 more
wiley   +1 more source

Nucleolar ribosomal RNA synthesis continues in differentiating lens fiber cells until abrupt nuclear degradation required for ocular lens transparency. [PDF]

RNA Biol
Rayêe D, Meier UT, Eliscovich C, Cvekl A.   +3 more
europepmc   +1 more source

Gut microbiota and tuberculosis

iMeta, EarlyView.
This review explores the intricate relationship between gut microbiota (GM) and tuberculosis (TB). The figure illustrates the bidirectional effects between GM dynamics and TB progression, as well as the interactions between the GM and antituberculosis drugs.
Yanhua Liu, Ling Yang, Maryam Meskini, Anjana Goel, Monique Opperman, Sagar Singh Shyamal, Ajay Manaithiya, Meng Xiao, Ruizi Ni, Yajing An, Mingming Zhang, Yuan Tian, Shuang Zhou, Zhaoyang Ye, Li Zhuang, Linsheng Li, Istuti Saraswat, Ankita Kar, Syed Luqman Ali, Shakir Ullah, Syed Yasir Ali, Shradha Kaushik, Tianmu Tian, Mingyang Jiao, Shujun Wang, Giulia Ghisleni, Alice Armanni, Sara Fumagalli, WenYu Wang, Chao Cao, Maria Carpena, Miguel A. Prieto, Antonia Bruno, Chanyuan Jin, Hanqing Hu, Yuhang Zhang, Ilse du Preez, Ashok Aspatwar, Lingxia Zhang, Wenping Gong   +39 more
wiley   +1 more source

Targeting interferon-stimulated gene of 20 kDa protein (Isg20) inhibits ribosome biogenesis to ameliorate the progression of renal fibrosis. [PDF]

PLoS One
Liu X, Wang H, Wang K, Liu Y.
europepmc   +1 more source

METTL5‐mediated 18S rRNA m6A modification enhances ribosome assembly and ABA response in Arabidopsis

iMeta, EarlyView.
METTL5 catalyzes the N6‐methyladenosine (m6A) methylation at A1771 in 18S rRNA, a modification essential for its association with the ribosomal protein RPL24A, facilitating the assembly of 80S ribosome. This facilitates the translation of mRNAs encoding the detoxifying glutathione S‐transferase (GST) enzymes, thereby maintaining normal reactive oxygen ...
Ping Li, Yu Zhang, Songyao Zhang, Jinqi Ma, Sheng Fan, Lisha Shen   +5 more
wiley   +1 more source

Prevalence and genetic diversity of Pentatrichomonas hominis in pig populations in Guangdong and Anhui Provinces, China. [PDF]

Parasite
Lu P, Zhu Y, Cai H, Shen H, Fang S, Wang D, Yan Z, Liao S, Qi N, Lv M, Lin X, Song Y, Chen X, Zhang J, Li J, Sun M.   +15 more
europepmc   +1 more source

Macrophage‐derived reactive oxygen species promote Salmonella aggresome formation contributing to bacterial antibiotic persistence

iMeta, EarlyView.
In this study, we reveal that macrophage‐derived reactive oxygen species (ROS) can trigger the rapid formation of Salmonella aggresomes, which substantially contribute to the increased frequency of persisters induced by phagocytosis. Salmonella containing aggresomes exhibited a dormant phenotype characterized by reduced adenosine triphosphate (ATP ...
Xiao Chen, Kefan Fang, Bo Li, Yingxing Li, Yuehua Ke, Weixin Ke, Tian Tian, Yifan Zhao, Linqi Wang, Jing Geng, Mark C. Leake, Fan Bai   +11 more
wiley   +1 more source

Environmental DNA analysis at multiple taxonomic levels highlights geographic variation in subtropical coastal marine communities. [PDF]

Sci Rep
Gibu K, Hamamoto K, Koeda K, Nishijima M, Kise H, Mizuyama M, Suzuki A, Aoki N, Yasuda N, Iguchi A.   +9 more
europepmc   +1 more source