Results 271 to 280 of about 138,758 (334)

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

International Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer, Morghan C. Lucas, Vitus Prokosch, Thomas Keßler, Thomas Risch, Andreas Laner, Jan Henkel, Anna Benet‐Pagès, Ariane Hallermayr, Verena Steinke‐Lange, Elke Holinski‐Feder, Barbara Klink   +11 more
wiley   +1 more source

Nested PCR as a superior diagnostic method for Acanthamoeba keratitis compared to conventional techniques. [PDF]

Sci Rep
Khaksar S, Latifi A, Mohebali M, Atighehchian M, Moradian A, Asadigandomani H, Rezaian M, Anasori N, Koosha M, Pellegrino K, Izadi S, Goudarzi F, Kazemirad E, Soleimani M.   +13 more
europepmc   +1 more source

Targeting Microbiome Metabolites: Reshaping Immunotherapy and Clinical Management Strategies for Colorectal Cancer

iMetaMed, EarlyView.
The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang, Ke Zhang, Lijie Xia, Jinyao Li   +3 more
wiley   +1 more source

Selection and evaluation of reference genes for quantitative real-time polymerase chain reaction normalization in Pieris melete (Lepidoptera, Pieridae). [PDF]

J Insect Sci
Jiang T, Liu X, Zou N, Zhang W, Peng Y, Xiao H.   +5 more
europepmc   +1 more source

Ribosomal RNA operon copy number: A trait‐informed framework to close the microbial cultivation gap

iMetaOmics, EarlyView.
The vast majority of microbes remain uncultured, constraining functional validation and limiting microbiome‐based applications. We show that ribosomal RNA operon (rrn) copy number—a stable, phylogenetically conserved genomic trait—is strongly correlated with cultivation outcomes across ecosystems.
Yuxiao Huang, Qingliu Wu, Chang Liu, Pugang Yu, Hao Li, Shengyue Tang, Fusuo Zhang, Shuangjiang Liu, Bin Ni   +8 more
wiley   +1 more source

Molecular characterization of tick genera Haemaphysalis, Ixodes, and Amblyomma in Korea. [PDF]

Parasites Hosts Dis
Lee S, Alkathiri B, Ahn KS, Kim J, Youn SY, Yoo MS, Lee HS, Kim JM, Kwak D, Shin SS, Lee SH.   +10 more
europepmc   +1 more source

Structure of the hepatitis C virus IRES bound to the human 80S ribosome: Remodeling of the HCV IRES [PDF]

, 2005
Boehringer, D., Lewis, J., Ostareck-Lederer, A., Stark, H., Thermann, R.   +4 more
core  

Diversity, transfer potential, and transcriptional activity of virus‐carried antibiotic resistance genes in global estuaries

iMetaOmics, EarlyView.
Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo, Xiyang Dong, Jia‑Ling Li, Ji‐Cheng Yao, Ziqi Peng, Qi Li, Zi‐Wen Yang, Yang Yuan, Wen‑Jun Li, Pandeng Wang   +9 more
wiley   +1 more source

Ribosomal protein Rps29/uS14 contributes to 18S rRNA maturation and its abundance regulates osmotic stress response in S. cerevisiae. [PDF]

Nucleic Acids Res
Zadali R, Tomecki R, Topf U.
europepmc   +1 more source

Majorbio Cloud 2026 provides comprehensive analysis workflows for microbiome

iMeta, EarlyView.
The integrated microbiome data analysis platform on Majorbio Cloud (https://cloud.majorbio.com/) encompasses 26 analytical workflows, with a core architecture of two modules: single‐omics workflows and cross‐omics integration and correlation workflows.
Jianhua Zhao, Linmeng Liu, Jichen Han, Junbiao Zhang, Xiaodan Li, Yan Wang, Qianhui Han, Xue Gong, Linna Zhang, Hao Gao, Bing Yang, Yachen Dong, Huasheng Huang, Xianglin Zhang, Kegang Yu   +14 more
wiley   +1 more source