Results 51 to 60 of about 46,527 (308)

Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA

open access: yes, 2012
Ribosomal RNA undergoes various modifications to optimize ribosomal structure and expand the topological potential of RNA. The most common nucleotide modifications in ribosomal RNA (rRNA) are pseudouridylations and 2'-O methylations (Nm), performed by H ...
Sharma, Sunny   +5 more
core   +1 more source

Evaluation of three molecular markers for identification of European primary parasitoids of cereal aphids and their hyperparasitoids. [PDF]

open access: yesPLoS ONE, 2017
Aphids are major pests of cereal crops and a suite of hymenopteran primary parasitoids play an important role in regulating their populations. However, hyperparasitoids may disrupt the biocontrol services provided by primary parasitoids.
Zhengpei Ye   +3 more
doaj   +1 more source

The Protist Ribosomal Reference database (PR2): a catalog of unicellular eukaryote Small Sub-Unit rRNA sequences with curated taxonomy [PDF]

open access: yes, 2012
The interrogation of genetic markers in environmental meta-barcoding studies is currently seriously hindered by the lack of taxonomically curated reference data sets for the targeted genes.
Probert, Ian   +35 more
core   +1 more source

Sandwich hybridisation assay for quantitative detection of yeast RNAs in crude cell lysates

open access: yesMicrobial Cell Factories, 2003
Background A rapid microtiter plate based sandwich hybridization assay was developed for detection and quantification of single RNA species using magnetic beads.
Molin Søren   +5 more
doaj   +1 more source

Loss of m1acp3Ψ Ribosomal RNA Modification Is a Major Feature of Cancer

open access: yesCell Reports, 2020
Summary: The ribosome is an RNA-protein complex that is essential for translation in all domains of life. The structural and catalytic core of the ribosome is its ribosomal RNA (rRNA).
Artem Babaian   +10 more
doaj   +1 more source

Rcl1 Protein, a Novel Nuclease for 18 S Ribosomal RNA Production [PDF]

open access: yesJournal of Biological Chemistry, 2011
In all forms of life, rRNAs for the small and large ribosomal subunit are co-transcribed as a single transcript. Although this ensures the equimolar production of rRNAs, it requires the endonucleolytic separation of pre-rRNAs to initiate rRNA production.
Darryl M, Horn   +2 more
openaire   +2 more sources

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Bowen–Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Psi1191 in yeast 18S rRNA

open access: yes, 2010
The Nep1 (Emg1) SPOUT-class methyltransferase is an essential ribosome assembly factor and the human Bowen–Conradi syndrome (BCS) is caused by a specific Nep1D86G mutation. We recently showed in vitro that Methanocaldococcus jannaschii Nep1 is a sequence-
Valeska Schilling   +27 more
core   +1 more source

18S ribosomal DNA-based PCR test for avian and mammalian DNA identification in meat products

open access: yesVeterinary and Animal Science, 2022
This work has aimed to create a PCR test to identify avian and mammalian DNA in meat products. The test is based on phylogenetic analysis of 18S ribosomal RNA (rRNA) of four major groups of Tetrapod: Amphibia, Reptilia, Mammalia, and Aves.
Irina M. Zyrianova, Oleg G. Zaripov
doaj   +1 more source

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