Validation of suitable internal control genes for expression studies in aging. [PDF]
, 2009 Quantitative data from experiments of gene expression are often normalized through levels of housekeeping genes transcription by assuming that expression of these genes is highly uniform. This practice is being questioned as it becomes increasingly clear
Bacalini, MARIA GIULIA +9 more
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Selection and evaluation of potential reference genes for gene expression analysis in Avena fatua
Plant Protection Science, 2019 Eight commonly used candidate reference genes, 18S ribosomal RNA (rRNA) (18S), 28S rRNA (28S), actin (ACT), glyceraldehyde-3-phosphate dehydrogenase (GAPDH), elongation factor 1 alpha (EF1α), ribosomal protein L7 (RPL7), Alpha-tubulin (α-TUB), and TATA ...
Junjie Liu +5 more
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Grass Snakes (Natrix natrix) as a Reservoir of Alaria alata and Other Parasites
Pathogens, 2022 The aim of the study was to investigate the occurrence of Alaria alata (Goeze, 1782) in fifty-one grass snakes (Natrix natrix) collected in Gostynińsko-Włocławski Landscape Park. Each snake was tested for the presence of A.
Aneta Bełcik +9 more
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Glutathione reductase-catalyzed cascade of redox reactions to bioactivate potent antimalarial 1,4-naphthoquinones--a new strategy to combat malarial parasites. [PDF]
, 2011 Our work on targeting redox equilibria of malarial parasites propagating in red blood cells has led to the selection of six 1,4-naphthoquinones, which are active at nanomolar concentrations against the human pathogen Plasmodium falciparum in culture and ...
Bauer, Holger +12 more
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PLoS Genetics, 2022 Ribosomes are essential nanomachines responsible for protein production. Although ribosomes are present in every living cell, ribosome biogenesis dysfunction diseases, called ribosomopathies, impact particular tissues specifically.
Jonathan Delhermite +9 more
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Next generation sequencing analysis reveals a relationship between rDNA unit diversity and locus number in Nicotiana diploids [PDF]
, 2012 © 2012 Matyášek et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Fulnecek, J +7 more
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Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in "Saccharomyces cerevisiae" [PDF]
, 2013 The 25S rRNA of yeast contains several base modifications in the functionally important regions. The enzymes responsible for most of these base modifications remained unknown.
Entian, Karl-Dieter +3 more
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Ribosomal Dysfunction Is a Common Pathomechanism in Different Forms of Trichothiodystrophy
Cells, 2023 Mutations in a broad variety of genes can provoke the severe childhood disorder trichothiodystrophy (TTD) that is classified as a DNA repair disease or a transcription syndrome of RNA polymerase II.
Gaojie Zhu +8 more
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Evaluating RNA status for RT-PCR in extracts of postmortem human brain tissue
BioTechniques, 2004 Total RNA was extracted from 105 individual postmortem human brain samples representing a range of postmortem conditions. To improve upon parameters currently used to screen for RNA quality, electropherogram patterns generated by the Agilent Bioanalyzer ...
Christine L. Miller +4 more
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Structural and functional analysis of Utp24, an endonuclease for processing 18S ribosomal RNA. [PDF]
PLoS ONE, 2018 The precursor ribosomal RNA is processed by multiple steps of nucleolytic cleavage to generate mature rRNAs. Utp24 is a PIN domain endonuclease in the early 90S precursor of small ribosomal subunit and is proposed to cleave at sites A1 and A2 of pre-rRNA.
Weidong An, Yifei Du, Keqiong Ye
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