Distant ribose 2'-O-methylation of 23S rRNA helix 69 pre-orders the capreomycin drug binding pocket at the ribosome subunit interface. [PDF]
Nandi S +4 more
europepmc +1 more source
ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo +5 more
wiley +1 more source
Anti-sense oligonucleotide probing as a structural platform for studying ribonucleoprotein complex assembly. [PDF]
Sheng K +6 more
europepmc +1 more source
Activation of toll‑like receptors by non‑coding RNAs and their fragments (Review). [PDF]
Esparza-Garrido RR +1 more
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Co-Selection of Antibiotic and Disinfectant Resistance in Bacteria Isolated from Reusable Blood Collection Tourniquets: Implications for Infection Control. [PDF]
Szymczyk J +3 more
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Novel features of Mycoplasma genitalium genomes identified through Oxford Nanopore sequence analysis of isolates from Australia. [PDF]
Huaman JL +7 more
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Genome-wide association studies builds a predictive model and reveals novel resistance features for macrolide-resistant Bordetella pertussis. [PDF]
Chen J, Liang G.
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Exploring GNRA tetraloop-like motifs in nucleic acid 3D structures. [PDF]
Bujnicki JM, Baulin EF.
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The binding of thiostrepton to 23S ribosomal RNA
Biochimie, 1991The antibiotic, thiostrepton, binds to 23S ribosomal RNA from E coli with a dissociation constant (KD) of 2.4 x 10(-7) M. The specificity of the interaction was established using 16S rRNA and modified or mutationally-altered 23S rRNA. Thus, no binding was detected with rRNA from the 30S subunit nor with rRNA modified in vitro by the thiostrepton ...
J, Thompson, E, Cundliffe
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23 s precursor ribosomal RNA of Rhodopseudomonas spherouides
Journal of Molecular Biology, 1970The bulk RNA of Rhodopseudomonas spheroides fails to show 23 s RNA when examined by either sucrose gradient sedimentation or polyacrylamide gel electrophoresis. Careful extraction of RNA by any of several techniques reveals ribosomal RNA's of three molecular weights: 5.3 × 105, 4.2 × 105 and 3.6 × 104 daltons, as determined by mobility on ...
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