Results 291 to 300 of about 93,732 (342)

Cost‐effectiveness of a tailored Helicobacter pylori eradication strategy based on the presence of a 23S ribosomal RNA point mutation that causes clarithromycin resistance in Korean patients

Journal of Gastroenterology and Hepatology, 2018
The Helicobacter pylori eradication rate using conventional triple therapy has decreased due to clarithromycin (CAM) resistance in H. pylori. Recently, dual priming oligonucleotide (DPO)‐based multiplex polymerase chain reaction (PCR) can be used to ...
Jun-Hyung Cho, S. Jeon, H. Kim, S. Jin, Suyeon Park   +4 more
semanticscholar   +1 more source

A hierarchical model for evolution of 23S ribosomal RNA

Nature, 2009
The emergence of the ribosome constituted a pivotal step in the evolution of life. This event happened nearly four billion years ago, and any traces of early stages of ribosome evolution are generally thought to have completely eroded away. Surprisingly, a detailed analysis of the structure of the modern ribosome reveals a concerted and modular scheme ...
Konstantin, Bokov, Sergey V, Steinberg
openaire   +2 more sources

Fragmentation heterogeneity of 23S ribosomal RNA in Haemophilus species

Gene, 1999
The fragmentation of 23S rRNA of 23 Haemophilus influenzae strains and eight strains belonging to other Haemophilus species was investigated. Instead of intact molecules, the 23S rRNA molecules were found to be cleaved into two to five smaller conserved fragments in most strains examined, especially in H. influenzae type b (5/6) and nontypeable strains
X M, Song, A, Forsgren, H, Janson
exaly   +3 more sources

Protein folding in Escherichia coli: role of 23S ribosomal RNA

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1999
Post-translational control of Escherichia coli ribosome on newly synthesised polypeptide leading to its active conformation (protein folding) has been shown in the case of the enzyme beta-galactosidase. As expected, antibiotics chloramphenicol and lincomycin, which bind to 23S rRNA/50S subunit and kasugamycin and streptomycin which interact with the ...
S, Chattopadhyay, S, Pal, D, Pal, D, Sarkar, S, Chandra, C, Das Gupta   +5 more
openaire   +2 more sources

Concerning the thermal stability of E. coli 23S ribosomal RNA

Biochimie, 1983
Total RNA prepared from E. coli by several extraction procedures behaves as a mixture of covalently continuous heat stable 23S, 16S and 4-5S components. 16S rRNA remains heat stable after isolation from such preparations, whereas isolated 23S rRNA is heat labile but becomes heat stable after EDTA treatment.
M F, Guérin, D, Hayes
openaire   +2 more sources

The excision of intervening sequences from salmonella 23S ribosomal RNA

Cell, 1990
Novel, approximately 90 bp intervening sequences (IVs) were discovered within the 23S rRNA genes of S. typhimurium and S. arizonae. These non-rRNA sequences are transcribed and then excised during rRNA maturation. The rRNA fragments that result from the excision of the extra sequences are not religated. This results in fragmented 23S rRNAs.
A B, Burgin, K, Parodos, D J, Lane, N R, Pace   +3 more
openaire   +2 more sources

Primary Structure Homology within the 23S Ribosomal RNA

Nature, 1968
OUR understanding of the evolution of the cell will depend largely on our gaining an understanding of the evolution of the cell's translation apparatus, and in this context I wish to discuss the recent finding that the RNA sequences (seen in a Tl ribonuclease digest) surrounding the methylated bases in the Escherichia coli 23S ribosomal RNA (rRNA) are ...
openaire   +2 more sources

Ribosomal activity of the 16 S · 23 S RNA complex

Archives of Biochemistry and Biophysics, 1985
It has been demonstrated in this laboratory that 16 S and 23 S RNAs form a binary complex like 30 S and 50 S ribosomes under certain specific conditions, and 5 S RNA can be incorporated into the complex in stoichiometric amounts in presence of three ribosomal proteins, L5, L18, and L15/25. These studies raised the basic question of whether such complex
D P, Burma, D S, Tewari, A K, Srivastava
openaire   +2 more sources

Co-transcription of 16S and 23S ribosomal RNA in Escherichia coli.

Nature New Biology, 1971
IF rifampicin is added to bacteria, RNA synthesis continues only for a short time, until all RNA molecules nascent at the time of addition of rifampicin are completed1,2. At times between 0 and 60 s after addition of rifampicin, we added3H-uridine to an exponential phase culture of E.
H. Bremer, L. Berry
semanticscholar   +3 more sources

Probing 23S Ribosomal RNA Cleavage Sites in Coccoid Helicobacter pylori

Helicobacter, 2001
ABSTRACTBackground.Previous studies have revealed that extensive nonrandom fragmentation of ribosomal RNA occurs during conversion of Helicobacter pylori to the coccoid form. The 16S rRNA fragmentation has been characterised in some detail. The aim of the present study was to define corresponding cleavage‐sites in the 3′‐half of the 23S rRNA molecule ...
H J, Monstein, C D, de la Cour, J, Jonasson   +2 more
openaire   +2 more sources