Results 131 to 140 of about 86,320 (269)

RNA N4‐acetylcytidine modification and its role in health and diseases

MedComm, Volume 6, Issue 1, January 2025.
N4‐acetylcytidine (ac4C) modification is a crucial RNA modification widely present in eukaryotic RNA. This review first outlines the latest research advancements on the roles and mechanisms of ac4C modification in both health and disease and explores ac4C‐targeted therapies with the aim of advancing cancer research and improving patient outcomes ...
Qiang Wang, Yixiao Yuan, Qiang Zhou, YingDong Jia, Jing Liu, GuangJun Xiao, Chunhong Li, Xiulin Jiang   +7 more
wiley   +1 more source

Rings Reconcile Genotypic and Phenotypic Evolution within the Proteobacteria. [PDF]

, 2015
Although prokaryotes are usually classified using molecular phylogenies instead of phenotypes after the advent of gene sequencing, neither of these methods is satisfactory because the phenotypes cannot explain the molecular trees and the trees do not fit
de la Haba, Rafael R, Koo, HyunMin, Lake, James A, Larsen, Joseph, Pu, Yiyi, Sarna, Brooke, Sinsheimer, Janet S, Zhao, Jun   +7 more
core   +2 more sources

The linked units of 5S rDNA and U1 snDNA of razor shells (Mollusca: Bivalvia: Pharidae) [PDF]

, 2011
[Abstract] The linkage between 5S ribosomal DNA and other multigene families has been detected in many eukaryote lineages, but whether it provides any selective advantage remains unclear.
A M González-Tizón, A Martínez-Lage, AM Domitrovich, AP Rooney, BM Tyler, C Branlant, CC Query, CL Will, D Bryant, D Posada, D Scherly, DC Cabral-de-Mello, DE Shippen-Lentz, DF Bogenhagen, DH Huson, DH Mathews, DL Swofford, DW Nelson, E Gornung, E Morzycka-Wroblewska, F Caradonna, F Pelliccia, G Drouin, I Cross, IL Hofacker, J Douet, J Felsestein, J Fernández-Tajes, J Vierna, J Vierna, J Vierna, JE Medlin, JS Reuter, K Brehm, K T Jensen, K Tamura, M Fernandez, M Fujiwara, M Manchado, M Marz, M Nei, M Úbeda-Manzanaro, MA Larkin, MZ Barciszewska, N Hernandez, N Hernandez, O Gascuel, P Cuello, P Librado, P Nguyen, P Richard, P Veltos, PCH Lo, PM Datson, R Barzotti, R Cosel von, R Cosel von, R Freire, R Giegerich, R Kalendar, RC Peterson, RD Little, S Cohen, S Guindon, S Sharp, S-H Chen, SJ Sharp, SM Mount, T Pieler, TA Hall, TH Eickbush, TL Bailey, Y Huang, Y Zhuang, Z Zamrod   +74 more
core   +2 more sources

Chromomycin A3 banding and chromosomal mapping of 45S and 5S ribosomal RNA genes in bottle gourd

Caryologia, 2021
Ribosomal DNAs and various banding patterns are landmarks in molecular cytogenetics providing useful information for karyotyping and addressing individual chromosomes.
Ahmet L. Tek, Hümeyra Yıldız, Kamran Khan, Bilge Ş. Yıldırım   +3 more
doaj  

Nascent polypeptide chains exit the ribosome in the same relative position in both eucaryotes and procaryotes. [PDF]

, 1983
We located the polypeptide nascent chain as it leaves cytoplasmic ribosomes from the plant Lemna gibba by immune electron microscopy using antibodies against the small subunit of the enzyme ribulose-1,5-bisphosphate carboxylase.
Bernabeu, C, Fowler, A, Lake, JA, Tobin, EM, Zabin, I   +4 more
core  

Glutathione reductase-catalyzed cascade of redox reactions to bioactivate potent antimalarial 1,4-naphthoquinones--a new strategy to combat malarial parasites.

, 2011
Our work on targeting redox equilibria of malarial parasites propagating in red blood cells has led to the selection of six 1,4-naphthoquinones, which are active at nanomolar concentrations against the human pathogen Plasmodium falciparum in culture and ...
Bauer, Holger, Brückner, Margit, Davioud-Charvet, Elisabeth, Deregnaucourt, Christiane, Jannack, Beate, Johann, Laure, Lanfranchi, Don Antoine, Lanzer, Michael, Müller, Tobias, Sanchez, Cecilia, Schirmer, R Heiner, Schrével, Joseph, Yardley, Vanessa   +12 more
core   +2 more sources

Nucleotide sequence of a 5S ribosomal RNA gene in the sea urchin Lytechinus variegatus [PDF]

, 1980
The nucleotide sequence of a cloned DNA fragment corresponding to a gene for 5S ribosomal RNA from the sea ...
Lu, A. Lien, Stafford, Darrel W., Steege, Deborah A.   +2 more
core   +2 more sources

Size, shape, and flexibility of RNA structures

, 2006
Determination of sizes and flexibilities of RNA molecules is important in understanding the nature of packing in folded structures and in elucidating interactions between RNA and DNA or proteins.
Cantor C. R., Changbong Hyeon, D. Thirumalai, Ruxandra I. Dima, Zuker M.   +4 more
core   +1 more source

Patterns and regulation of ribosomal RNA transcription in Borrelia burgdorferi

BMC Microbiology, 2011
Background Borrelia burgdorferi contains one 16S and two tandem sets of 23S-5S ribosomal (r) RNA genes whose patterns of transcription and regulation are unknown but are likely to be critical for survival and persistence in its hosts. Results RT-PCR of B.
Schwartz Ira, Godfrey Henry P, Bugrysheva Julia V, Cabello Felipe C   +3 more
doaj   +1 more source

Reduced ribosomal RNA expression and unchanged ribosomal DNA promoter methylation in oral squamous cell carcinoma

Molecular Genetics & Genomic Medicine, 2019
Background Ribosomal RNA (rRNA) consists of four non‐coding RNAs, the 28S, 5.8S, 18S, and 5S rRNA. Abnormal expression of rRNA has been found in multiple tumors, and the methylation of rDNA promoter may affect rRNA expression as an epigenetic regulatory ...
Shanshan Ha, Hong Zhou, Mayank Gautam, Yaling Song, Changning Wang   +4 more
doaj   +1 more source