Results 191 to 200 of about 26,439 (217)

Comparative studies on bacterial 5S ribosomal RNA

Archives of Biochemistry and Biophysics, 1973
Abstract The 5S rRNAs of Escherichia coli , Bacillus stearothermophilus , and B. subtilis were isolated and their molecular conformation examined. All three 5S rRNAs were similar with regard to nucleotide chain length, base composition and general configuration.
P N, Gray, G F, Saunders
openaire   +2 more sources

The involvement of 5S RNA in the binding of tRNA to ribosomes

Biochemical and Biophysical Research Communications, 1973
Abstract The tRNA fragment TpψpCpGp was found to bind to 5S RNA. This binding is ten times increased when a specific 5S RNA-protein complex is used. The ability of TpψpCpGp to bind to the complex could be abolished by selective chemical modification of two adenines in 5S RNA.
V A, Erdmann, M, Sprinzl, O, Pongs
openaire   +2 more sources

The Evolutionary History of the Structure of 5S Ribosomal RNA

Journal of Molecular Evolution, 2009
5S rRNA is the smallest nucleic acid component of the large ribosomal subunit, contributing to ribosomal assembly, stability, and function. Despite being a model for the study of RNA structure and RNA-protein interactions, the evolution of this universally conserved molecule remains unclear. Here, we explore the history of the three-domain structure of
Feng-Jie, Sun, Gustavo, Caetano-Anollés
openaire   +2 more sources

The nucleotide sequence of chicken 5S ribosomal RNA

Journal of Molecular Evolution, 1974
The nucleotide sequence of the 5S ribosomal RNA of somatic cells of the chicken (Gallus gallus) differs from that of other vertebrates thus far examined. Besides base substitutions, alterations include two nucleotide deletions and two additions.
N R, Pace, T A, Walker, B, Pace, R L, Erikson   +3 more
openaire   +2 more sources

Role of 5S ribosomal RNA in polypeptide synthesis

Biochemical and Biophysical Research Communications, 1969
50S ribosomes obtained from Escherichia coli dissociated by dialysis into 5S rRNA and 44S particles, noting partially uncoiled ...
M A, Siddiqui, K, Hosokawa
openaire   +2 more sources

Promoter region for yeast 5S ribosomal RNA

Nature, 1977
WE have sequenced the DNA region immediately preceding the structural gene for the 5S ribosomal RNA of yeast (Saccharomyces cerevisiae). Since the 5S RNA, a component of the larger ribosomal subunit, has a 5′ triphosphate1,2, this molecule is likely to be the direct product of the gene, unmodified by maturation at the 5′ end.
A M, Maxam, R, Tizard, K G, Skryabin, W, Gilbert   +3 more
openaire   +2 more sources

Gapmer Antisense Oligonucleotides Targeting 5S Ribosomal RNA Can Reduce Mature 5S Ribosomal RNA by Two Mechanisms

Nucleic Acid Therapeutics, 2020
In this study, we demonstrate that 5S ribosomal RNA (rRNA), a highly structured and protein-bound RNA, is quite difficult to reduce with antisense oligonucleotides (ASOs). However, we found a single accessible site that was targetable with a high-affinity complementary ASO. The ASO appeared to bind to the site, recruit RNaseH1, and cause degradation of
Adam J, Pollak, Justin H, Hickman, Xue-Hai, Liang, Stanley T, Crooke   +3 more
openaire   +2 more sources

Role of 5S ribosomal RNA in polypeptide synthesis. II. Dissociation of 5S ribosomal RNA from 50S ribosomes in Escherichiacoli

Biochemical and Biophysical Research Communications, 1968
SOS ribosomes obtained from E. coli were dissociated into 5s rRNA and -44s particles in which at least one of the protein components was missing. Dissociation was produced by dialysis vs. 0.5 M NH4Cl in Mg++-free medium and the resulting 44s particles were isolated by centrifugation through Mg’+-free sucrose solution.
M A, Siddiqui, K, Hosokawa
openaire   +2 more sources

Metabolism of 5S RNA in the absence of ribosome production

Cell, 1974
Abstract The results presented in this report show that during early development of Xenopus laevis the synthesis of 5S RNA occurs in blastula embryos, whereas the synthesis of 18S and 28S RNA cannot be detected until gastrulation. Thus the initiation of synthesis of the three ribosomal RNAs is not coordinate during early development.
openaire   +2 more sources

Transcription of Xenopus 5S ribosomal RNA genes

Nature, 1982
The accurate transcription of 5S RNA genes when injected into the nucleus of Xenopus oocytes or when added to an in vitro transcription system has allowed identification of the DNA sequences and one of the protein factors required for 5S RNA synthesis.
openaire   +2 more sources