Results 51 to 60 of about 86,320 (269)

Distribution of dwell times of a ribosome: effects of infidelity, kinetic proofreading and ribosome crowding [PDF]

Physical Biology, 8 (2011) 026005, 2010
Ribosome is a molecular machine that polymerizes a protein where the sequence of the amino acid residues, the monomers of the protein, is dictated by the sequence of codons (triplets of nucleotides) on a messenger RNA (mRNA) that serves as the template. The ribosome is a molecular motor that utilizes the template mRNA strand also as the track. Thus, in
arxiv   +1 more source

Molecular Mechanism of DNA Topoisomerase I-Dependent rDNA Silencing: Sir2p Recruitment at Ribosomal Genes [PDF]

, 2016
Saccharomyces cerevisiae sir2Δ or top1Δ mutants exhibit similar phenotypes involving ribosomal DNA, including (i) loss of transcriptional silencing, resulting in non-coding RNA hyperproduction from cryptic RNA polymerase II promoters; (ii) alterations ...
Bjornsti, Mary Ann, Camilloni, Giorgio, Carlini, Valentina, D'Alfonso, Anna, DI FELICE, Francesca, Hertz, Marla I, Wright, Christine M   +6 more
core   +1 more source

UPF201 archaeal specific family members reveal structural similarity to RNA-binding proteins but low likelihood for RNA-binding function. [PDF]

PLoS ONE, 2008
We have determined X-ray crystal structures of four members of an archaeal specific family of proteins of unknown function (UPF0201; Pfam classification: DUF54) to advance our understanding of the genetic repertoire of archaea. Despite low pairwise amino
Krishnamurthy N Rao, Stephen K Burley, Subramanyam Swaminathan   +2 more
doaj   +1 more source

Stochastic theory of protein synthesis and polysome: ribosome profile on a single mRNA transcript [PDF]

Journal of Theoretical Biology, vol.289, 36-46 (2011), 2011
The process of polymerizing a protein by a ribosome, using a messenger RNA (mRNA) as the corresponding template, is called {\it translation}. Ribosome may be regarded as a molecular motor for which the mRNA template serves also as the track. Often several ribosomes may translate the same (mRNA) simultaneously.
arxiv   +1 more source

Dynamics of ribosomes in mRNA translation under steady and non-steady state conditions [PDF]

Phys. Rev. E 101, 062404 (2020), 2020
Recent advances in DNA sequencing and fluorescence imaging have made it possible to monitor the dynamics of ribosomes actively engaged in messenger RNA (mRNA) translation. Here, we model these experiments within the inhomogeneous totally asymmetric simple exclusion process (TASEP) using realistic kinetic parameters.
arxiv   +1 more source

Operon conservation and the evolution of trans-splicing in the phylum Nematoda [PDF]

, 2006
The nematode Caenorhabditis elegans is unique among model animals in that many of its genes are cotranscribed as polycistronic pre-mRNAs from operons.
Bektesh, Bektesh, Blaxter, Blaxter, Blaxter, Blaxter, Blaxter, Blumenthal, Blumenthal, Blumenthal, Bonen, David B. Guiliano, Davis, Davis, De Ley, Dufourcq, Evans, Evans, Ganot, Ghedin, Gomez-Escobar, Goyal, Guiliano, Hu, Huang, Koltai, Koltai, Krause, Kroiher, Kuersten, Kuwabara, Lall, Landfear, Lee, Lindh, Liu, Maere, Mark L. Blaxter, Nilsen, Nilsen, Page, Parkinson, Parkinson, Pouchkina-Stantcheva, Redmond, Satou, Speith, Stein, Stover, Vandenberghe, Vanfleteren, Whitton, Williams, Zorio   +53 more
core   +7 more sources

The first complete genome sequence of the class Fimbriimonadia in the phylum Armatimonadetes. [PDF]

PLoS ONE, 2014
In this study, we present the complete genome of Fimbriimonas ginsengisoli Gsoil 348T belonging to the class Fimbriimonadia of the phylum Armatimonadetes, formerly called as candidate phylum OP10. The complete genome contains a single circular chromosome
Zi-Ye Hu, Yue-Zhu Wang, Wan-Taek Im, Sheng-Yue Wang, Guo-Ping Zhao, Hua-Jun Zheng, Zhe-Xue Quan   +6 more
doaj   +1 more source

Anti-replicative recombinant 5S rRNA molecules can modulate the mtDNA heteroplasmy in a glucose-dependent manner. [PDF]

PLoS ONE, 2018
Mutations in mitochondrial DNA are an important source of severe and incurable human diseases. The vast majority of these mutations are heteroplasmic, meaning that mutant and wild-type genomes are present simultaneously in the same cell. Only a very high
Romuald Loutre, Anne-Marie Heckel, Damien Jeandard, Ivan Tarassov, Nina Entelis   +4 more
doaj   +1 more source

Location of single-stranded and double-stranded regions in rat liver ribosomal 5S RNA and 5.8S RNA.

Nucleic Acids Research, 1981
Rat liver 5S rRNA and 5.8S rRNA were end-labelled with 32P at 5'-end or 3'-end of the polynucleotide chain and partially digested with single-strand specific S1 nuclease and double-strand specific endonuclease from the cobra Naja naja oxiana venom.
I. Toots, A. Metspalu, R. Villems, M. Saarma   +3 more
semanticscholar   +1 more source

5S Ribosomal RNA genes of the newt Notophthalmus viridescens [PDF]

Nucleic Acids Research, 1981
The genes which code for the 5S ribosomal RNA in the newt, Notophthalmus viridescens have been cloned and analyzed. Two types of repeating unit were detected: a major type consisting of a 120 bp coding region with a 111 bp spacer, and a minor type composed of a coding region, a pseudogene, and a 113 bp spacer.
B K Kay, Joseph G. Gall
openaire   +3 more sources