Results 51 to 60 of about 40,749 (233)

DCAF13 Safeguards Hematopoietic Stem Cells via RRS1‐Regulated Ribosome Biogenesis

Advanced Science, EarlyView.
This study establishes DCAF13 as an essential regulator for hematopoietic stem cell (HSC) function. Its deletion in mice causes lethal pancytopenia and HSC depletion. Mechanistically, DCAF13 interacts with RRS1 and mediates its non‐degradative K27‐linked ubiquitination, thereby stabilizing RRS1 to maintain ribosome biogenesis and protein translation ...
Mengke Li, Yuxin Wu, Shuai Zhou, Peipei Tang, Jiaming Wei, Ling Liu, Zhenyi Wang, Deyang Shi, Shengnan Yuan, Qingyu Zhang, Shihui Wang, Qing Zhang, Huan Zhao, Rui Zhang, Yingying Wang, Shiwei Yang, Xiangli Chen, Xiaojing Shi, Guangzhi Liu, Yuwei Zhang, Jinming Li, Xu Dong Zhang, Rick F Thorne, Dongping Wei, Zumin Zhu, Song Chen   +25 more
wiley   +1 more source

Clustering of bacteria by the triplet composition of 5S RNA [PDF]

ITM Web of Conferences
The relationship between the structure of nucleotide sequences, the function they encode, and the taxonomy of the host is an important subject of study for molecular biologists and bioinformaticians, as well as specialists in processing big data arrays ...
Ovchinnikova Iuliia, Sadovsky Michael, Sokolov Vladislav   +2 more
doaj   +1 more source

Representation, searching and discovery of patterns of bases in complex RNA structures [PDF]

We describe a graph theoretic method designed to perform efficient searches for substructural patterns in nucleic acid structural coordinate databases using a simplified vectorial representation.
Artymiuk, P.J., Harrison, A-M., South, D.R., Willett, P.   +3 more
core   +1 more source

Ribozyme für die RNA‐katalysierte Methylierung und Markierung von RNA

Angewandte Chemie, EarlyView.
Ribozyme sind vielseitige Werkzeuge für die präzise Modifikation von RNA. Das Reaktionsspektrum in‐vitro‐selektierter Ribozyme reicht vom Einbau funktioneller Gruppen und Fluorophoren bis zu natürlichen RNA‐Methylierungen. Dieser Übersichtsartikel präsentiert Cofaktor‐abhängige Ribozyme für die positionsgenaue Markierung und Modifikation von RNA ...
Carolin P. M. Scheitl, Claudia Höbartner   +1 more
wiley   +1 more source

5S ribosomal RNA database

, 2016
Ribosomal 5S RNA (5S rRNA) is a conserved component of the large subunit of all cytoplasmic and the majority of organellar ribosomes in all organisms.  5SRNAdb is the first database that provides a high quality reference set of ribosomal 5S RNAs across three domains of life.
Szymanski, Maciej, Zielezinski, Andrzej, Karlowski, Wojciech   +2 more
openaire   +1 more source

Overexpression of a Brix Domain-Containing Ribosome Biogenesis Factor ARPF2 and its Interactor ARRS1 Causes Morphological Changes and Lifespan Extension in Arabidopsis thaliana

Frontiers in Plant Science, 2018
The Brix domain is a conserved domain in several proteins involved in ribosome biogenesis in yeast and animals. In the Arabidopsis genome, six Brix domain-containing proteins are encoded; however, their molecular functions have not been fully ...
Shugo Maekawa, Yoshiaki Ueda, Shuichi Yanagisawa   +2 more
doaj   +1 more source

Rings Reconcile Genotypic and Phenotypic Evolution within the Proteobacteria. [PDF]

, 2015
Although prokaryotes are usually classified using molecular phylogenies instead of phenotypes after the advent of gene sequencing, neither of these methods is satisfactory because the phenotypes cannot explain the molecular trees and the trees do not fit
de la Haba, Rafael R, Koo, HyunMin, Lake, James A, Larsen, Joseph, Pu, Yiyi, Sarna, Brooke, Sinsheimer, Janet S, Zhao, Jun   +7 more
core   +2 more sources

Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling

Angewandte Chemie International Edition, EarlyView.
Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl, Claudia Höbartner   +1 more
wiley   +1 more source

Integrated genomic and transcriptomic approaches reveal oxidative stress adaptation mechanisms in a mesotrione‐resistant Amaranthus tuberculatus biotype

Pest Management Science, EarlyView.
Integrated GWAS and transcriptomics in a Canadian waterhemp biotype reveal mesotrione resistance is polygenic and metabolically driven. Significant SNPs and 187 herbicide‐responsive genes point to enhanced redox homeostasis, glutathione‐linked detoxification, lipid/secondary metabolism, and oxidative stress responses. Resistance arises from coordinated,
Martin Laforest, Marianne Bessette, Geneviève Gagnon, Sandra Flores‐Mejia, Brahim Soufiane, Marie‐Claire Goulet, Dominique Michaud   +6 more
wiley   +1 more source

THE SYNTHESIS OF 5S RIBOSOMAL RNA DURING POLLEN DEVELOPMENT [PDF]

Development, Growth and Differentiation, 1975
Tradescantia paludosa 5S ribosomal RNA (rRNA) has been characterized with respect to its base composition and relative electrophoretic mobility in comparison with that of E. coli. The period of 5S rRNA synthesis during pollen grain development was determined by pulse labeling the RNA synthesized during a 24 hr period of development with 32 P and then ...
Lorraine B, Peddada, Joseph P, Mascarenhas   +1 more
openaire   +2 more sources