Results 171 to 180 of about 484,088 (306)

Emerging roles of ribosome translation in stem cells and stem cell therapy - a review. [PDF]

Cell Biosci
Gao Y, Guo L, Shi G, Wang R, Wang X, Lou J.   +5 more
europepmc   +1 more source

The FindMNDBiomarker Program: Protein Changes in Motor Neuron Disease/Amyotrophic Lateral Sclerosis Postmortem Tissue and Biofluids

Annals of Neurology, EarlyView.
Objective Biomarkers of disease pathogenesis are critically needed for amyotrophic lateral sclerosis (ALS) to facilitate diagnosis and patient stratification into appropriate therapeutic trials. Proteomic studies offer significant potential to advance this, but reproducibility across laboratories is a key component toward identifying protein changes ...
Gabrielle L. Adler, Matthew C. Kiernan, Rachel H. Tan   +2 more
wiley   +1 more source

Stem loop binding protein promotes SARS-CoV-2 replication via -1 programmed ribosomal frameshifting. [PDF]

Signal Transduct Target Ther
Chen T, Zhu R, Du T, Yang H, Zhang X, Wang Z, Zhang Y, Quan W, Yin B, Liu Y, Lu S, Peng X.   +11 more
europepmc   +1 more source

Potential Application of a Water‐Soluble Fullerene C60 Decorated with Diethylene Glycol in Treatment of Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
A new ethoxyethanol derivative of iminofullerene, F2, is synthesized and labeled with 99mTc to produce 99mTc‐F2. In vitro, compound F2 inhibits the activation of primary mouse bone marrow‐derived macrophages stimulated with lipopolysaccharide. Moreover, 99mTc‐F2 is selectively enriched in the injured joints of mice. Inflammatory macrophages play a role
Rui He, Alyssa Costello, Yanjie Liu, Weicheng Wang, Zhichang Zhang, Quanjun Cui, Xinlin Yang   +6 more
wiley   +1 more source

Non-variable RNA deletion using the CRISPR-Cas9 technique demonstrated improved outcomes in human intestine single-cell RNA sequencing data, even at half sequencing depths. [PDF]

Genomics Inform
Kim DJ, Joh CSY, Jeong SY, Kim YJ, Koh SJ, Kim HJ.   +5 more
europepmc   +1 more source

Graphene Oxide‐Based Gene Modulation in Preferential Elimination of Lung Cancer Cells in a 3D Tumor Microenvironment Model

Advanced NanoBiomed Research, EarlyView.
Chemically modified graphene oxide nanocarriers provide a targeted lung cancer gene therapy platform. In a 3D tumor microenvironment model, these nanocarriers deliver therapeutic genes, regulate immune markers, and induce apoptosis in cancer cells. Combined gene delivery enhances cancer cell elimination, demonstrating the potential of this approach for
Francesca Grilli, Sadman Sakib, Fabio Variola, Shan Zou   +3 more
wiley   +1 more source

Doublet decoding of tRNA^Ser3 demonstrates plasticity of ribosomal decoding center. [PDF]

Nat Commun
Krishnaswamy S, Akbar S, Larsson DSD, Chen Y, Selmer M.   +4 more
europepmc   +1 more source

Inconsistencies in the published rabbit ribosomal rRNAs: a proposal for uniformity in sequence and site numbering. [PDF]

RNA
De S, Zhou M, Brown ZP, Burton-Smith RN, Hashem Y, Pestova TV, Hellen CUT, Frank J.   +7 more
europepmc   +1 more source

Genomic Insights Into a Strong Biofilm‐Forming Enterococcus faecalis MTR_EFS01 Strain Isolated From a Shrimp in Bangladesh

Animal Research and One Health, EarlyView.
This study characterizes a multidrug‐resistant and strong biofilm‐forming Enterococcus faecalis strain obtained from a shrimp sample in Bangladesh. ABSTRACT Enterococcus faecalis is known for its ability to form strong biofilms and its role as an opportunistic pathogen. In this study, we screened and characterized a multidrug‐resistant (MDR) and strong
Md. Ashek Ullah, Md. Saiful Islam, Md. Liton Rana, Jayedul Hassan, Md. Tanvir Rahman   +4 more
wiley   +1 more source

Bacterial ribosome heterogeneity facilitates rapid response to stress. [PDF]

J Bacteriol
Shen Y-L, Xu L, Zhou Y, Ye B-C.
europepmc   +1 more source