Results 11 to 20 of about 5,035,452 (301)

Platelets and tumor-associated RNA transfer.

Blood, 2021
Until recently the nucleic acid content of platelets was considered to be fully determined by their progenitor megakaryocyte. However, it is now well understood that additional mediators (e.g.
Silvia D’Ambrosi, J. Nilsson, T. Wurdinger   +2 more
semanticscholar   +2 more sources

Schwann cell-like differentiated adipose stem cells promote neurite outgrowth via secreted exosomes and RNA transfer [PDF]

Stem Cell Res Ther, 2018
Adipose derived stem cells can be stimulated to produce a growth factor rich secretome which enhances axon regeneration. In this study we investigated the importance of exosomes, extracellular vesicles released by many different cell types, including ...
Rosanna C Ching, M. Wiberg, P. Kingham
semanticscholar   +2 more sources

Structural signatures of thermal adaptation of bacterial ribosomal RNA, transfer RNA, and messenger RNA. [PDF]

PLoS ONE, 2017
Temperature adaptation of bacterial RNAs is a subject of both fundamental and practical interest because it will allow a better understanding of molecular mechanism of RNA folding with potential industrial application of functional thermophilic or ...
Clara Jegousse, Yuedong Yang, Jian Zhan, Jihua Wang, Yaoqi Zhou   +4 more
doaj   +2 more sources

Smuggling on the Nanoscale—Fusogenic Liposomes Enable Efficient RNA-Transfer with Negligible Immune Response In Vitro and In Vivo [PDF]

Pharmaceutics, 2023
The efficient and biocompatible transfer of nucleic acids into mammalian cells for research applications or medical purposes is a long-standing, challenging task.
Marco Hoffmann, Sven Gerlach, Masanari Takamiya, Samar Tarazi, Nils Hersch, Agnes Csiszár, Ronald Springer, Georg Dreissen, Hanno Scharr, Sepand Rastegar, Tanja Beil, Uwe Strähle, Rudolf Merkel, Bernd Hoffmann   +13 more
doaj   +2 more sources

A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA

Nature Communications, 2020
Extracellular vesicles (EV) facilitate intercellular transfer of biological material including RNA, but the regulatory mechanisms for their formation and transfer are incompletely known.
Olivier G. de Jong, Daniel E. Murphy, Imre Mäger, Eduard Willms, Antonio Garcia-Guerra, Jerney J. Gitz-Francois, Juliet Lefferts, Dhanu Gupta, Sander C. Steenbeek, Jacco van Rheenen, Samir El Andaloussi, Raymond M. Schiffelers, Matthew J. A. Wood, Pieter Vader   +13 more
doaj   +2 more sources

Transfer RNA-derived small RNAs in the cancer transcriptome [PDF]

Pflügers Archiv: European Journal of Physiology, 2016
The cellular lifetime includes stages such as differentiation, proliferation, division, senescence and apoptosis.These stages are driven by a strictly ordered process of transcription dynamics.
A Dueck, A Sobala, AE Hall, AM Burroughs, C Cole, C Fricke, D Green, D Haussecker, D Kim, Darrell Green, DM Thompson, DP Bartel, DR Rhodes, FE Nicolas, GL Hager, H Fu, H Goodarzi, I Salaverria, JM Perkel, M Ghildiyal, M Talpaz, MS Pagter de, NC Schopman, O Rechavi, P Adjibade, P Ivanov, P Kumar, P Kumar, Q Wang, R Levitz, RL Maute, S Yamasaki, SC Stearns, T Uchiumi, Tamas Dalmay, U Harms, William D. Fraser, YS Lee, Z Li   +38 more
core   +2 more sources

The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer [PDF]

Cell, 2018
E. Pastuzyn, C. Day, Rachel B. Kearns, Madeleine Kyrke-Smith, Andrew V. Taibi, John McCormick, Nathan Yoder, D. Belnap, S. Erlendsson, D. Morado, J. Briggs, C. Feschotte, J. Shepherd   +12 more
semanticscholar   +3 more sources

RNA secondary structure prediction using an ensemble of two-dimensional deep neural networks and transfer learning

Nature Communications, 2019
The limited availability of high-resolution 3D RNA structures for model training limits RNA secondary structure prediction. Here, the authors overcome this challenge by pre-training a DNN on a large set of predicted RNA structures and using transfer ...
Jaswinder Singh, Jack Hanson, Kuldip Paliwal, Yaoqi Zhou   +3 more
doaj   +2 more sources

PltRNAdb: Plant transfer RNA database.

PLoS ONE, 2022
Transfer RNAs (tRNAs) are intermediate-sized non-coding RNAs found in all organisms that help translate messenger RNA into protein. Recently, the number of sequenced plant genomes has increased dramatically.
Morad M Mokhtar, Achraf El Allali
doaj   +3 more sources

Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture

eLife, 2023
Full-length mRNAs transfer between adjacent mammalian cells via direct cell-to-cell connections called tunneling nanotubes (TNTs). However, the extent of mRNA transfer at the transcriptome-wide level (the ‘transferome’) is unknown.
Sandipan Dasgupta, Daniella Y Dayagi, Gal Haimovich, Emanuel Wyler, Tsviya Olender, Robert H Singer, Markus Landthaler, Jeffrey E Gerst   +7 more
doaj   +1 more source