Results 11 to 20 of about 911,945 (298)

Transfer RNA and Origins of RNA Interference [PDF]

Frontiers in Molecular Biosciences, 2021
Almost 30 years ago the first microRNA (miRNA) was detected (Lee et al., 1993), later put in mechanistical context by the discovery of the RNA interference (RNAi) and RNA-induced silencing complex (RISC). miRNA is the variable RISC element (guide) that recognizes messenger RNA (mRNA) targets in the RNAi process facilitated by Argonaute (Ago) proteins ...
Andrey Grigoriev
doaj   +4 more sources

Structural signatures of thermal adaptation of bacterial ribosomal RNA, transfer RNA, and messenger RNA. [PDF]

PLoS ONE, 2017
Temperature adaptation of bacterial RNAs is a subject of both fundamental and practical interest because it will allow a better understanding of molecular mechanism of RNA folding with potential industrial application of functional thermophilic or ...
Clara Jegousse, Yuedong Yang, Jian Zhan, Jihua Wang, Yaoqi Zhou   +4 more
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Smuggling on the Nanoscale—Fusogenic Liposomes Enable Efficient RNA-Transfer with Negligible Immune Response In Vitro and In Vivo [PDF]

Pharmaceutics, 2023
The efficient and biocompatible transfer of nucleic acids into mammalian cells for research applications or medical purposes is a long-standing, challenging task.
Marco Hoffmann, Sven Gerlach, Masanari Takamiya, Samar Tarazi, Nils Hersch, Agnes Csiszár, Ronald Springer, Georg Dreissen, Hanno Scharr, Sepand Rastegar, Tanja Beil, Uwe Strähle, Rudolf Merkel, Bernd Hoffmann   +13 more
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Crystal structures and snapshots along Tpt1-catalyzed phosphate transfer from nucleic acid to NAD+ [PDF]

Nature Communications
Tpt1/TRPT1/KptA family proteins are evolutionarily conserved in all three domains of life. In fungi and plants, Tpt1 transfers 2’-PO4 2- from tRNA splice junction to NAD+, which is the final step of tRNA maturation and is critical for the function of ...
Chulei Cao, Jie Yang, Weizhen Zhang, Jiaqin Chen, Yanqing Gao, Yuqi Yao, Yixi Zhang, Huili Li, Linxi Li, Zhaorong Luo, Chenxi Wang, Guangli Tang, Ruixue Cui, Hehua Liu, Qiyao Wang, Zhen Huang, Jinbiao Ma, Jianhua Gan   +17 more
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Mechanisms of Transfer RNA Fragments Functionality Within and Between Cells and Organisms [PDF]

Cells
Transfer RNA-derived fragments (tRFs) have become a significant category of small non-coding RNAs that likely play vital roles in various cellular functions.
Sathyanarayanan Vaidhyanathan, Yan X. Lin, Adesupo A. Adetowubo, Fatmanur Kiliç, Sai Anusha Jonnalagadda, Andrey Grigoriev   +5 more
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PltRNAdb: Plant transfer RNA database

PLoS ONE, 2022
Transfer RNAs (tRNAs) are intermediate-sized non-coding RNAs found in all organisms that help translate messenger RNA into protein. Recently, the number of sequenced plant genomes has increased dramatically.
Morad M. Mokhtar, Achraf EL Allali
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Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture

eLife, 2023
Full-length mRNAs transfer between adjacent mammalian cells via direct cell-to-cell connections called tunneling nanotubes (TNTs). However, the extent of mRNA transfer at the transcriptome-wide level (the ‘transferome’) is unknown.
Sandipan Dasgupta, Daniella Y Dayagi, Gal Haimovich, Emanuel Wyler, Tsviya Olender, Robert H Singer, Markus Landthaler, Jeffrey E Gerst   +7 more
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Bacterial transfer RNAs [PDF]

FEMS Microbiology Reviews, 2015
Transfer RNA is an essential adapter molecule that is found across all three domains of life. The primary role of transfer RNA resides in its critical involvement in the accurate translation of messenger RNA codons during protein synthesis and, therefore, ultimately in the determination of cellular gene expression.
Shepherd, Jennifer, Ibba, Michael
openaire   +3 more sources

Exogenous RNA as a Regulatory Signal during a Plant’s Interaction with the Biotic Environment: An Evolutionary Perspective and Future Applications in Agriculture

Plants, 2021
Environmental RNAi (eRNAi) is a sequence-specific regulation of endogenous gene expression in a responsive organism by exogenous RNA. While exogenous RNA transfer between organisms of different kingdoms of life have been unambiguously identified in ...
Sergey Ivashuta, Alberto Iandolino, Greg Watson   +2 more
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Myosin-Va-dependent cell-to-cell transfer of RNA from Schwann cells to axons. [PDF]

PLoS ONE, 2013
To better understand the role of protein synthesis in axons, we have identified the source of a portion of axonal RNA. We show that proximal segments of transected sciatic nerves accumulate newly-synthesized RNA in axons.
José R Sotelo, Lucía Canclini, Alejandra Kun, José R Sotelo-Silveira, Lei Xu, Horst Wallrabe, Aldo Calliari, Gonzalo Rosso, Karina Cal, John A Mercer   +9 more
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