Results 31 to 40 of about 925,090 (301)

Direct activation of RNA polymerase III transcription by c-Myc

, 2003
The proto-oncogene product c-Myc has a direct role in both metazoan cell growth and division. RNA polymerase III (pol III) is involved in the generation of transfer RNA and 5S ribosomal RNA, and these molecules must be produced in bulk to meet the need ...
Eisenman, R.N., Gomez-Roman, N., Grandori, C,, White, R.J.   +3 more
core   +1 more source

Microguards and micromessengers of the genome [PDF]

, 2016
The regulation of gene expression is of fundamental importance to maintain organismal function and integrity and requires a multifaceted and highly ordered sequence of events.
A Bobrie, A Gioti, A Leiblich, A Lukasik, A Sharma, A Weiberg, AE Hall, AH Buck, B-C Yoo, C Braicu, C Fricke, D Green, D Haig, D Kim, DJ Sharkey, DM Pegtel, DP Bartel, E Marin-Gonzalez, E Tili, G Arnqvist, GL Hager, H Liu, H Valadi, H Zhou, J Lotvall, J Skog, JA Andres, JM Perkel, JR Chevillet, JS Parent, K Ohshima, K Sun, K Wang, L Corrigan, L Vojtech, LA McGraw, LA McGraw, LK Sirot, M Ghildiyal, M Greaves, M Mittelbrunn, MK Lawniczak, ML Squadrito, NS Barteneva, O Rechavi, P Cayirlioglu, P Kumar, P Xu, PB Medawar, PS Mitchell, S Mathivanan, S Sarker, S Weilner, S Wigby, S Wigby, T Chapman, T Chapman, T Chapman, T Chapman, T Chapman, T Dalmay, T Dalmay, T Kogure, TE Swingler, VN Kim, W Filipowicz, WX Chen, X Chen, Y Lee, Y Ouyang   +69 more
core   +1 more source

Transfer RNA-derived small RNAs in tumor microenvironment

Molecular Cancer, 2023
Transfer RNAs (tRNAs) are a class of non-coding RNAs responsible for amino acid translocation during protein synthesis and are ubiquitously found in organisms.
Mei Yang, Yongzhen Mo, Daixi Ren, Shun Liu, Zhaoyang Zeng, Wei Xiong   +5 more
doaj   +1 more source

Cold Induction of EARLI1, a Putative Arabidopsis Lipid Transfer Protein, Is Light and Calcium Dependent [PDF]

, 2004
As sessile organisms, plants must adapt to their environment. One approach toward understanding this adaptation is to investigate environmental regulation of gene expression.
Comai L., Gleave A.P., Henriksson K.N., Lee I., Murashige T., Sambrook J., Sukumaran N.P., Wang H., Wirtz K.W.   +8 more
core   +2 more sources

Highly efficient in vitro and in vivo delivery of functional RNAs using new versatile MS2-chimeric retrovirus-like particles

Molecular Therapy: Methods & Clinical Development, 2015
RNA delivery is an attractive strategy to achieve transient gene expression in research projects and in cell- or gene-based therapies. Despite significant efforts investigating vector-directed RNA transfer, there is still a requirement for better ...
Anne Prel, Vincent Caval, Régis Gayon, Philippe Ravassard, Christine Duthoit, Emmanuel Payen, Leila Maouche-Chretien, Alison Creneguy, Tuan Huy Nguyen, Nicolas Martin, Eric Piver, Raphaël Sevrain, Lucille Lamouroux, Philippe Leboulch, Frédéric Deschaseaux, Pascale Bouillé, Luc Sensébé, Jean-Christophe Pagès   +17 more
doaj   +1 more source

Electron Transfer in Proteins [PDF]

, 1996
Electron-transfer (ET) reactions are key steps in a diverse array of biological transformations ranging from photosynthesis to aerobic respiration. A powerful theoretical formalism has been developed that describes ET rates in terms of two parameters ...
Gray, Harry B., Winkler, Jay R.
core   +1 more source

Impact of template backbone heterogeneity on RNA polymerase II transcription. [PDF]

, 2014
Variations in the sugar component (ribose or deoxyribose) and the nature of the phosphodiester linkage (3'-5' or 2'-5' orientation) have been a challenge for genetic information transfer from the very beginning of evolution.
Chong, Jenny, Huang, Xuhui, Wang, Dong, Wang, Wei, Xu, Liang, Zhang, Lu   +5 more
core   +1 more source

Analysis of extracellular RNA by digital PCR

Frontiers in Oncology, 2014
The transfer of extracellular RNA is emerging as an important mechanism for intracellular communication. The ability for the transfer of functionally active RNA molecules from one cell to another within vesicles such as exosomes enables a cell to ...
Kenji eTakahashi, Irene K Yan, Chaeyoung eKim, Jungsu eKim, Tushar ePatel   +4 more
doaj   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Extensive horizontal gene transfer in cheese-associated bacteria. [PDF]

, 2017
Acquisition of genes through horizontal gene transfer (HGT) allows microbes to rapidly gain new capabilities and adapt to new or changing environments.
Bonham, Kevin S, Dutton, Rachel J, Wolfe, Benjamin E   +2 more
core   +3 more sources