Transfer RNA-derived small RNA: an emerging small non-coding RNA with key roles in cancer
Transfer RNAs (tRNAs) promote protein translation by binding to the corresponding amino acids and transporting them to the ribosome, which is essential in protein translation.
Xinliang Gu +5 more
doaj +1 more source
Small RNAs and extracellular vesicles in filarial nematodes: from nematode development to diagnostics [PDF]
Parasitic nematodes have evolved sophisticated mechanisms to communicate with their hosts in order to survive and successfully establish an infection. The transfer of RNA within extracellular vesicles (EVs) has recently been described as a mechanism that
Babayan, S.A. +2 more
core +3 more sources
Multiple effects of silymarin on the hepatitis C virus lifecycle [PDF]
Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo.
Bourne, Nigel +16 more
core +1 more source
Sequence organization of feline leukemis virus DNA in infected cells [PDF]
A restriction site map has been deduced of unintegrated and integrated FeLV viral DNA found in human RD cells after experimental infection with the Gardner-Arnstein strain of FeLV.
Casey, James W. +3 more
core +1 more source
ER Membrane Contact Sites: Key Platforms for Biogenesis of RNA-Containing Extracellular Vesicles
The mechanisms by which cytoplasmic cargoes such as RNAs are incorporated into extracellular vesicles (EVs) are poorly understood. In a recent article published in Developmental Cell, we describe a novel function of endoplasmic reticulum membrane contact
Bahnisikha Barman +2 more
doaj +1 more source
Highly Sensitive Northern Hybridization Using a Rapid Protocol for Downward Alkaline Blotting of RNA
A simple and fast RNA gel blot procedureis described that uses 50 mM NaOH tosimultaneously transfer and fix RNA to apositively charged nylon membrane. TheRNA is transferred in a downward direction,and transfer is routinely completedwithin 2.5 h.
Ivan L. Ingelbrecht +2 more
doaj +1 more source
Model-guided design of ligand-regulated RNAi for programmable control of gene expression [PDF]
Progress in constructing biological networks will rely on the development of more advanced components that can be predictably modified to yield optimal system performance.
Chase L Beisel +4 more
core +5 more sources
Biosynthetic pathway of mitochondrial ATPase subunit 9 in Neurospora crassa [PDF]
Subunit 9 of mitochondrial ATPase (Su9) is synthesized in reticulocyte lysates programmed with Neurospora poly A-RNA, and in a Neurospora cell free system as a precursor with a higher apparent molecular weight than the mature protein (Mr 16,400 vs.
Hennig, Bernd +3 more
core +1 more source
Characterization of UVA-Induced Alterations to Transfer RNA Sequences
Ultraviolet radiation (UVR) adversely affects the integrity of DNA, RNA, and their nucleoside modifications. By employing liquid chromatography–tandem mass spectrometry (LC–MS/MS)-based RNA modification mapping approaches, we identified the transfer RNA (
Congliang Sun +2 more
doaj +1 more source
The complete mitogenome sequence of Sinogastromyzon szechuanensis was obtained using next generation sequencing and confirmed via overlap-PCR method.
Wei Li +7 more
doaj +1 more source

