Untranslated Nucleotide Sequence at the 5′-End of R 17 Bacteriophage RNA
Nature, 1970The 5′-terminal sequence of 74 nucleotides reported here does not seem to be involved in the synthesis of phage specific proteins but is probably concerned in the replication of R17 RNA. It is also of comparative interest—the sequence is strikingly similar to the corresponding section of Qβ phage RNA.
J M, Adams, S, Cory
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Genetic complementation of radiation response by 3 untranslated regions (UTR) of RNA
International Journal of Radiation Biology, 1996The molecular basis of radiosensitivity was studied using a cDNA complementation approach to correct radiosensitivity in cells. Four cDNAs of sizes 1.6, 2.0, 2.2 and 2.5 kb were isolated that corrected several aspects of the phenotype of cells from patients with the human genetic disorder ataxia-telangiectasia, characterized by hypersensitivity to ...
Chen, P. +10 more
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An initiation signal in the 5′ untranslated leader sequence of encephalomyocarditis virus RNA
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1990A 593 nucleotide fragment of the 5' leader of encephalomyocarditis virus RNA (EMCV-RNA) was linked to the SP6 promoter and inserted upstream of the reporter gene chloramphenicol acetyltransferase (CAT). The presence of the 5'-UTR of EMCV-RNA in the RNA transcripts, made in vitro with the SP6 polymerase, resulted in a strong translational enhancement ...
Oudshoorn, P +3 more
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Global estimation of the 3′ untranslated region landscape using RNA sequencing
Methods, 2015The 3' untranslated region (3' UTR) of mRNA contains elements that play regulatory roles in polyadenylation, localization, translation efficiency, and mRNA stability. Despite the significance of the 3' UTR, there is no popular method for annotating 3' UTRs and for profiling their isoforms. Recently, poly(A)-position profiling by sequencing (3P-seq) and
MinHyeok, Kim, Bo-Hyun, You, Jin-Wu, Nam
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Evidence of putative non-coding RNAs from Leishmania untranslated regions
Molecular and Biochemical Parasitology, 2017Non-coding RNAs (ncRNAs) are regulatory elements present in a wide range of organisms, including trypanosomatids. ncRNAs transcribed from the untranslated regions (UTRs) of coding genes have been described in the transcriptomes of several eukaryotes, including Trypanosoma brucei. To uncover novel putative ncRNAs in two Leishmania species, we examined a
Felipe, Freitas Castro +5 more
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Untranslated vesicular stomatitis virus messenger RNA after poliovirus infection
Virology, 1977Superinfection of vesicular stomatitis virus (VSV)-infected cells with poliovirus causes a complete inhibition of VSV-directed protein synthesis, followed by normal replication of poliovirus. The “shut-off” of VSV protein synthesis appears similar in all respects to the inhibition of host cell protein synthesis normally induced by poliovirus infection.
E, Ehrenfeld, H, Lund
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Molecular Cloning and Sequence Analysis of a Human Untranslated Alu-Containing RNA
DNA Sequence, 2001A cDNA, designated LNX1, has been identified by subtractive hybridization on the basis that it is expressed in normal human prostate but not in LNCaP cells. Sequence analysis revealed that it contained two Alu repetitive sequences but no long open reading frame. Hence, it belongs to a class of untranslated Alu-containing RNAs. LNX1 is expressed in most
S C, Kwok, I, Daskal
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Implication of CcpN in the regulation of a novel untranslated RNA (SR1) in Bacillus subtilis
Molecular Microbiology, 2005Summary Antisense‐RNAs have been investigated in detail over the past 20 years as the principal regulators in accessory DNA elements such as plasmids, phages and transposons. However, only a few examples of chromosomally encoded bacterial antisense RNAs were known. Meanwhile, ≈70 small non‐coding RNAs from the
Andreas, Licht +2 more
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We have isolated a cDNA clone after reverse transcription of the genomic RNA of Asibi yellow fever virus whose structure suggests it was formed by self-priming from a 3'-terminal hairpin of 87 nucleotides in the genomic RNA. We have also isolated a clone from cDNA made to Murray Valley encephalitis virus RNA that also appears to have arisen by self ...
Hahn, Chang S. +6 more
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Inhibition of tumorigenicity by the 5′-untranslated RNA of the human c-myc P0 transcript
Experimental Cell Research, 2003Activity of the independently regulated human c-myc P0 promoter has been associated with the undifferentiated status of leukemia cells as well as the hormone-independent proliferation of breast cancer cells. The P0 transcript is distinguished from the predominant P1 and P2 c-myc mRNAs by an approximately 639-nucleotide extension of the 5'-untranslated ...
Scott W, Blume +11 more
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