Results 261 to 270 of about 158,881 (313)

Exosomal miR‐4644 Targets SPRY3 to Promote Proliferation and Invasion of Pancreatic Cancer

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Tumor‐derived exosomes (TDEs) can carry diverse genetic material that modulates pancreatic cancer (PC) proliferation and invasion. Despite this, the involvement of microRNAs (miRNAs) in TDE‐mediated tumor progression in PC remains inadequately explored. Methods Ultracentrifugation was used to isolate exosomes derived from AsPC‐1 and
Xiangyu Chu   +8 more
wiley   +1 more source

Importance of the 3'UTR region in globin synthesis: identification of two novel HBA1 mutations causing α-Thalassemia. [PDF]

open access: yesAnn Hematol
Benito SF   +8 more
europepmc   +1 more source

Exosome‐mediated miR‐4660 delivery inhibits OPN promoted hepatoma cells aggression through targeting LGALS3BP

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
miR‐4660 was found to be downregulated in exosomes derived from SMMC‐OPN cells, a stable HCC cell line that overexpresses OPN. LGALS3BP has been identified as a direct target of miR‐4660, with its expression levels elevated in both SMMC‐OPN cells and their secreted exosomes.
Cuihua Liu   +9 more
wiley   +1 more source

LncRNA MIR503HG serves as a diagnostic biomarker in patients with sepsis and regulates sepsis‐induced inflammation and cardiac dysfunction

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
MIR503HG was downregulated in sepsis and sepsis‐induced cardiac dysfunction (SICD) and served as a diagnostic biomarker. Overexpression of MIR503HG attenuated myocardial injury and systemic inflammation in a septic rat model. Mechanistically, MIR503HG acted as a ceRNA by sponging miR‐497‐5p to upregulate BDNF, revealing a protective MIR503HG/miR‐497‐5p/
Pingping Qi   +5 more
wiley   +1 more source

Synergistic Interaction Between MALAT1/miR‐30b‐5p/BAFF Axis and Inflammatory Cytokines Underlies Rituximab‐Refractory NMOSD

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
The MALAT1/miR‐30b‐5p/BAFF axis is activated in monocytes during NMOSD onset and relapse. The MALAT1/miR‐30b‐5p/BAFF axis is activated in monocytes, thereby facilitating the release of BAFF and inflammatory cytokines (including IL‐1, IL‐6, IL‐8, and TNF‐α).
Meiqun Deng   +8 more
wiley   +1 more source

Hepatitis C Virus 5'UTR Sequences That Bind eIF3 and Ribosomal 40S Subunits Confer Stimulation of Minus-Strand RNA Synthesis. [PDF]

open access: yesInt J Mol Sci
Malik AQ   +8 more
europepmc   +1 more source

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