Results 181 to 190 of about 2,365,116 (344)

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

The 5S RNA binding protein from yeast (Saccharomyces cerevisiae) ribosomes [PDF]

, 1984
M. Yaguchi, C. F. Rollin, C. Roy, R. N. Nazar   +3 more
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Identity of the RNA-binding protein K of hnRNP particles with protein H16, a sequence-specific single strand DNAbinding protein [PDF]

, 1994
Claire Gaillard, Éric Cabannes, François Strauss   +2 more
openalex   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

The binding of ribosomal protein S4 does not change the gross conformation of the 16 S RNA.

, 1979
S.H. Allen, K.P. Wong
openalex   +1 more source

Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis

Nature Protocols, 2014
M. J. Moore, Chaolin Zhang, Emily C. Gantman, Aldo Mele, J. Darnell, R. Darnell   +5 more
semanticscholar   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Nucleotide sequences of two adjacent M or M-like protein genes of group A streptococci: different RNA transcript levels and identification of a unique immunoglobulin A-binding protein [PDF]

, 1992
Debra E. Bessen, V A Fischetti
openalex   +1 more source

RNA-Binding Protein Dnd1 Inhibits MicroRNA Access to Target mRNA

Cell, 2007
M. Kedde, Markus Strasser, Bijan Boldajipour, J. O. Vrielink, Krasimir Slanchev, Carlos le Sage, Remco Nagel, P. Voorhoeve, Josyanne J A van Duijse, U. A. Ørom, A. Lund, A. Perrakis, E. Raz, R. Agami   +13 more
semanticscholar   +1 more source