Results 211 to 220 of about 1,877,035 (363)

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

KH-R3H domain cooperation in RNA recognition by the global RNA-binding protein KhpB. [PDF]

Nat Commun
Fukui K, Murakawa T, Baba S, Kumasaka T, Yano T.   +4 more
europepmc   +1 more source

RNA binding protein MSI2 positively regulates FLT3 expression in myeloid leukemia

, 2017
Ayuna Hattori, Daniel McSkimming, Natarajan Kannan, Takahiro Ito   +3 more
openalex   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

SERBP1: A Multifunctional RNA-Binding Protein Linking Gene Expression, Cellular Metabolism, and Diseases. [PDF]

Cells
Ji Z, Ablimit A.
europepmc   +1 more source

Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III.

, 1993
Chao-Ming Chiang, Hui Ge, Zhiqiang Wang, Alexander Hoffmann, Robert G. Roeder   +4 more
openalex   +2 more sources

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Unveiling ELAVL1 as a key RNA-binding protein regulating the chemokine signaling pathway in diabetic nephropathy. [PDF]

Biochem Biophys Rep
Hosseini SA, Ajorlou P, Bandsariyan A, Sohrabipour S.   +3 more
europepmc   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Targeted RNAi screen reveals novel regulators of RNA-binding protein phase transitions in Caenorhabditis elegans oocytes. [PDF]

G3 (Bethesda)
Elaswad MT, Thomas GM, Hays C, Trombley NJ, Schisa JA.   +4 more
europepmc   +1 more source