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Design of RNA-binding proteins and ligands
Current Opinion in Structural Biology, 2001The rapidly expanding database of RNA structures and protein complexes is beginning to lead to the successful design of specific RNA-binding molecules. Recent combinatorial and structure-based approaches have utilized known nucleic-acid-binding scaffolds from both proteins and small molecules to display a relatively small set of functional groups often
Alan C. Cheng+2 more
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Motif models for RNA-binding proteins
Current Opinion in Structural Biology, 2018Identifying the binding preferences of RNA-binding proteins (RBPs) is important in understanding their contribution to post-transcriptional regulation. Here, we review the current state-of-the art of RNA motif identification tools for RBPs. New in vivo and in vitro data sets provide sufficient statistical power to enable detection of relatively long ...
Alexander Sasse+3 more
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Single stranded RNA binding proteins
Current Opinion in Structural Biology, 2000Our knowledge of protein interactions with RNA molecules has been, so far, largely restricted to cases in which the RNA itself is folded into a secondary and/or tertiary structure stabilised by intramolecular base pairing and stacking. Until recently, only limited structural information has been available about protein interactions with single-stranded
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RNA binding proteins in epilepsy
Gene Function & Disease, 2001RNA binding proteins are involved in a diverse array of biological functions including mRNA transport, splicing, localization, stability and translation. Jerky is an RNA binding protein, complexed with mRNAs in neurons, that regulates mRNA utilization and consequently translation.
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Structures of RNA-binding proteins
Quarterly Reviews of Biophysics, 1997Jean Cavarelli, John G. Arnez
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Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma
Nature, 1993A. Crozat, P. Åman, N. Mandahl, D. Ron
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The RNA-binding protein repertoire of embryonic stem cells
Nature Structural &Molecular Biology, 2013S. -. Kwon+10 more
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