Results 171 to 180 of about 1,640,882 (289)

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Beyond transcription: RNA-binding proteins steering angiogenesis. [PDF]

Am J Physiol Heart Circ Physiol
Hamm K, Clifford E, Kozak KN, Cullison J, Iqbal H, Yan R, Xing Y, Liu Z.   +7 more
europepmc   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

RNA-binding proteins connect Exon usage to the chromatin. [PDF]

NAR Genom Bioinform
Robertson H, Do HTT, Helms V.
europepmc   +1 more source

Abstract 2087 Characterizing 14-3-3 proteins as putative RNA Polymerase II binding proteins [PDF]

Haley A. Hardtke, Brendan J. Floyd, Edward M. Marcotte, Yan Zhang   +3 more
openalex   +1 more source

The RNA Binding Domains of the Nuclear poly(A)-binding Protein [PDF]

, 2003
Uwe Kühn, Anne Németh, Sylke Meyer, Elmar Wahle   +3 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Reviewer #3 (Public Review): IQCH regulates spermatogenesis by interacting with CaM to promote the expression of RNA-binding proteins

Tiechao Ruan, Ruixi Zhou, Yihong Yang, Junchen Guo, Chuan Jiang, Xiang Wang, Gan Shen, Siyu Dai, Su‐Ren Chen, Ying Shen   +9 more
openalex   +2 more sources

RNA-binding proteins orchestrating immunity in plants. [PDF]

Plant J
Bach-Pages M, Menon A, Wadley B, Castello A, Preston GM.   +4 more
europepmc   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source