3D‐Printed Unibody Microfluidic Devices for Organ‐on‐Chip Applications
Advanced Materials Technologies, EarlyView.A practical approach is demonstrated to 3D printing unibody microfluidic Organ‐on‐Chip (OoC) devices using commercial resins and desktop DLP printers. The demonstrated functional devices support 2D monolayers, 3D spheroids, and barrier tissues. With optimised design and post‐processing techniques, leak‐free, biocompatible microchannels and membranes ...
Louis Jun Ye Ong +8 more
wiley +1 more source
Polymerase Mu Is a DNA-Directed DNA/RNA Polymerase [PDF]
, 2003 Stephanie A. Nick McElhinny +1 more
openalex +3 more sources
NUCLEAR RNA POLYMERASE D1 is essential for tomato embryogenesis and desiccation tolerance in seeds
Cell ReportsSummary: Plant-unique RNA polymerase IV (RNA Pol IV) governs the establishment of small RNA (sRNA)-directed DNA methylation (RdDM). In dicotyledon, elevated RdDM activity is often associated with embryogenesis; however, the loss of RdDM frequently ...
Yixuan Feng +3 more
doaj
Single molecule studies on the dynamics of the transcription initiation complex of yeast mitochondria [PDF]
, 2017 Department of Biomedical EngineeringThe transcription initiation complex in the yeast mitochondria of Saccharomyces cerevisiae comprises the RNA polymerase, Rpo41, the initiation factor, Mtf1, and the DNA including 6 base pair promoter sequence. The Mtf1
Cho, Hayoon
core
Nanomaterial‐Based Optical Biosensors for SARS‐CoV‐2 Detection: A Retrospective of the Pandemic
Advanced Sensor Research, EarlyView.This review discusses nanomaterial‐based optical biosensors developed for or adapted to the detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). It concludes by providing a perspective on how lessons learned during the coronavirus disease of 2019 (COVID‐19) pandemic may be applied for future research on nanomaterial‐based ...
Flavie Martin +2 more
wiley +1 more source
RNA-Dependent DNA Polymerase Activity of RNA Tumor Viruses II. Directing Influence of RNA in the Reaction [PDF]
, 1972 Jonathan Leis, Jerard Hurwitz
openalex +1 more source
Mutations in Mtr4 Structural Domains Reveal Their Important Role in Regulating tRNA\u3csub\u3ei\u3c/sub\u3e \u3csup\u3eMet\u3c/sup\u3e Turnover in \u3cem\u3eSaccharomyces cerevisiae\u3c/em\u3e and Mtr4p Enzymatic Activities \u3cem\u3eIn Vitro\u3c/em\u3e [PDF]
, 2016 RNA processing and turnover play important roles in the maturation, metabolism and quality control of a large variety of RNAs thereby contributing to gene expression and cellular health.
Anderson, James T. +2 more
core +1 more source
Advanced Science, EarlyView.Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu +14 more
wiley +1 more source
Medicine in Novel Technology and DevicesMycobacterium tuberculosis (Mtb) is responsible for the spread of tuberculosis (TB). The current study employed virtual screening of 2569 natural compounds against the DNA-directed RNA polymerase (RNAP) of Mtb to identify the possible binders that can ...
Ehssan H. Moglad
doaj
RNA-Dependent DNA Polymerase Activity of RNA Tumor Viruses I. Directing Influence of DNA in the Reaction [PDF]
, 1972 Jerard Hurwitz, Jonathan Leis
openalex +1 more source