Results 301 to 310 of about 325,869 (333)

Foxc1 regulates Pecam-1 Expression in embryonic Endothelial Progenitor Cells [PDF]

, 2008
Lamparter, Mathias
core  

Liver-directed base editing of <i>ABCC6</i> prevents ectopic calcification in a variant-humanized mouse model of pseudoxanthoma elasticum. [PDF]

Mol Ther Nucleic Acids
Testa LC, Obiri-Yeboah D, Said H, Qu P, Levine MA, Alameh MG, Musunuru K, Li Q, Wang X.   +8 more
europepmc   +1 more source

Structural Insights into De Novo Promoter Escape by Mycobacterium tuberculosis RNA Polymerase. [PDF]

Nat Commun
Brewer J, Delbeau M, Zoullas WB, Darst SA, Campbell EA.   +4 more
europepmc   +1 more source

GC Content and Thermal Stability of Double-Stranded RNA: Fragments of Microsporidia <i>Vairimorpha ceranae</i> and <i>Nosema bombycis</i> AT-Rich Genes Are Sensitive to Standard Heat Treatment. [PDF]

Int J Mol Sci
Fadeev RR, Timofeev SA, Senderskiy IV, Dolgikh VV.   +3 more
europepmc   +1 more source

The MTORC1 signaling pathway related gene POLR3G serves as a potential prognostic biomarker in Hepatocellular Carcinoma. [PDF]

Clin Exp Med
Wang Z, Chen J, Zhang B, Rong Y, Wu D, Ji R.   +5 more
europepmc   +1 more source

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Cycling of RNA-directed DNA polymerase on natural and synthetic RNA templates

Nature, 1976
RNA-DIRECTED DNA polymerase (reverse transcriptase) catalyses in vivo the synthesis of DNA complementary to the RNA of tumour viruses. The DNA is integrated into the host genome and is therefore implicated in the subsequent tumorigenesis1. The mechanism by which reverse transcriptase replicates the viral RNA into complementary DNA (cDNA) and its ...
L J, Krueger, G V, Weiss, W C, Merrick, M A, Lloyd, W F, Anderson   +4 more
openaire   +2 more sources

Atypical RNA polymerase subunits required for RNA-directed DNA methylation

Nature Genetics, 2005
RNA-directed DNA methylation, one of several RNA interference-mediated pathways in the nucleus, has been documented in plants and in human cells. Despite progress in identifying the DNA methyltransferases, histone-modifying enzymes and RNA interference proteins needed for RNA-directed DNA methylation, the mechanism remains incompletely understood.
Tatsuo, Kanno, Bruno, Huettel, M Florian, Mette, Werner, Aufsatz, Estelle, Jaligot, Lucia, Daxinger, David P, Kreil, Marjori, Matzke, Antonius J M, Matzke   +8 more
openaire   +2 more sources

Comparison of RNA-directed DNA polymerases from xenotropic and ecotropic viruses

Biochemical and Biophysical Research Communications, 1975
Summary RNA-directed DNA polymerases from several xenotropic and ecotropic type-C murine viruses were compared. On sedimentation velocity gradients polymerases from Rauscher murine leukemia virus, AT-124 virus, New Zealand Black virus, and BALB: virus 2 appeared at identical positions as single peaks.
Strickland, J E, Fowler, A K, Hellman, A
openaire   +2 more sources

Synthesis of Sindbis virus complementary DNA by avian myeloblastosis virus RNA-directed DNA polymerase

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1978
Sindbis virus 42 S RNA was efficiently transcribed into complementary DNA (CDNA) by avian myeloblastosis virus alphabeta DNA polymerase using oligo- (dT) or single-stranded calf thymus DNA as primers. Both of the Sindbis virus cDNA products were able to protect 60% of 125I-labeled Sindbis virus RNA, at near equal weight ratios, from RNAase A and T1 ...
V, Yuferov, D P, Grandgenett, M, Bondurant, C, Riggin, M, Tigges   +4 more
openaire   +2 more sources

Innate Reverse Transcriptase Activity of DNA Polymerase for Isothermal RNA Direct Detection

Journal of the American Chemical Society, 2015
RNA detection has become one of the most robust parts in molecular biology, medical diagnostics and drug discovery. Conventional RNA detection methods involve an extra reverse transcription step, which limits their further application for RNA rapid detection.
Chao, Shi, Xiaotong, Shen, Shuyan, Niu, Cuiping, Ma   +3 more
openaire   +2 more sources