Results 61 to 70 of about 582,722 (350)
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
trumpet: transcriptome-guided quality assessment of m6A-seq data
BMC Bioinformatics, 2018 Background Methylated RNA immunoprecipitation sequencing (MeRIP-seq or m6A-seq) has been extensively used for profiling transcriptome-wide distribution of RNA N6-Methyl-Adnosine methylation.
Teng Zhang +3 more
doaj +1 more source
L-GIREMI uncovers RNA editing sites in long-read RNA-seq
Genome Biology, 2023 Although long-read RNA-seq is increasingly applied to characterize full-length transcripts it can also enable detection of nucleotide variants, such as genetic mutations or RNA editing sites, which is significantly under-explored.
Zhiheng Liu +7 more
doaj +1 more source
NBLDA: Negative Binomial Linear Discriminant Analysis for RNA-Seq Data
, 2015 RNA-sequencing (RNA-Seq) has become a powerful technology to characterize gene expression profiles because it is more accurate and comprehensive than microarrays. Although statistical methods that have been developed for microarray data can be applied to
Dong, Kai +3 more
core +1 more source
ROCK signalling induced gene expression changes in mouse pancreatic ductal adenocarcinoma cells [PDF]
, 2016 The RhoA and RhoC GTPases act via the ROCK1 and ROCK2 kinases to promote actomyosin contraction, resulting in directly induced changes in cytoskeleton structures and altered gene transcription via several possible indirect routes.
Clark, William +3 more
core +1 more source
The Comparison between Bulk RNA-seq and Ssingle-cell RNA-seq
Journal of Physics: Conference Series, 2021 Abstract Bulk RNA-seq and single cell RNA-seq (Sc-RNA) seq are two well-known methods and are broadly used in biology areas. Even though the two ways are all starting from the mRNA level to do the transcriptional analysis, many differences still show in them, but the differences which are critical for researchers to judge and consider ...
openaire +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
BioengineeringRNA sequencing (RNA-seq) has emerged as a prominent resource for transcriptomic analysis due to its ability to measure gene expression in a highly sensitive and accurate manner.
Farhana Manzoor +2 more
doaj +1 more source
Dissecting intratumoral myeloid cell plasticity by single cell RNA‐seq
Cancer Medicine, 2019 Tumor‐infiltrating myeloid cells are the most abundant leukocyte population within tumors. Molecular cues from the tumor microenvironment promote the differentiation of immature myeloid cells toward an immunosuppressive phenotype.
Qianqian Song +19 more
doaj +1 more source
An observation of circular RNAs in bacterial RNA-seq data [PDF]
, 2016 Circular RNAs (circRNAs) are a class of RNA with an important role in micro RNA (miRNA) regulation recently discovered in Human and various other eukaryotes as well as in archaea.
Aurell, Erik +3 more
core +1 more source