Results 271 to 280 of about 2,860,779 (318)

Architecture of RNA–RNA interactions

Current Opinion in Genetics & Development, 2022
RNA molecules tend to form intricate tertiary structures via intramolecular RNA-RNA interactions (RRIs) to regulate transcription, RNA processing, and translation processes. In these biological processes, RNAs, especially noncoding RNAs, usually achieve their regulatory specificity through intermolecular RNA-RNA base pairing and execute their ...
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RNA Editing with Viral RNA-Dependent RNA Polymerase

ACS Synthetic Biology, 2022
RNA editing is currently attracting attention as a method for editing genetic information without injury to the genome. The most common approach to edit RNA sequences involves the induction of an A-to-I change by adenosine deaminase acting on RNA (ADAR). However, this method only allows point editing.
Shinzi Ogasawara, Ai Yamada
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RNA-dependent RNA polymerases in RNA silencing

Biological Chemistry, 2011
Abstract RNA-dependent RNA polymerases (RdRPs) synthesize double-stranded RNAs that are processed into small RNAs and mediate gene silencing. Viral RdRPs and cellular RdRPs show little structural homology to each other. Cellular RdRPs play key roles in RNA silencing by producing complementary strands for target RNAs via Dicer-dependent and -
Yoshiko, Maida, Kenkichi, Masutomi
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RNA Libraries and RNA Recognitiona

Annals of the New York Academy of Sciences, 1996
Random RNA libraries, consisting of > 10(13) unique sequences, contain molecules capable of specifically binding small molecule and protein ligands by noncovalent interaction. Successive steps of affinity purification and amplification allow the propagation and eventual isolation of specific binding molecules, called aptamers.
F J, Schmidt, B, Cho, H B, Nicholas
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Nanostructured RNAs for RNA Interference

2014
We synthesized three types of nanostructured RNAs that induce RNA interference (RNAi): branched RNAs, dumbbell-shaped RNA, and circular double-stranded RNAs. All three nanostructured RNAs were transformed into double-stranded RNA of approximately 20 base pairs when they were treated with nuclease enzymes such as Dicer.
Yuko, Nakashima, Naoko, Abe, Yoshihiro, Ito, Hiroshi, Abe   +3 more
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RNA–RNA SELEX

2014
Systematic evolution of ligands by exponential enrichment (SELEX) protocol is a valuable technique to identify RNA aptamers interacting with RNA structural motifs. RNA aptamers are mainly resolved with affinity column chromatography and electrophoretic mobility shift assay (EMSA).
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