Results 291 to 300 of about 4,315,290 (339)

YY1 Interacts with Promoter R-Loops to Regulate Transcription. [PDF]

J Am Chem Soc
He X, Yuan J, Li L, Gao Z, Wang Y.
europepmc   +1 more source

Impact of RNA Lipid Particle Aggregates on the Tumor Microenvironment in a Murine Brain Tumor Model

Hector Mendez-Gomez
openalex   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Cas10 residues lining the target RNA binding channel regulate interference by distinguishing cognate target RNA from mismatched targets. [PDF]

RNA Biol
Khweis SA, Blackburn MA, Perdigao CC, Pierce MO, Lewis CR, Dunkle JA.   +5 more
europepmc   +1 more source

Author response: ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins

Mathew J. Thayer, Michael B. Heskett, Leslie G. Smith, Paul T. Spellman, Phillip A. Yates   +4 more
openalex   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Decoding RNA-protein interactions using high-throughput methods. [PDF]

RNA Biol
Régis M, Pulcina P, Kretov DA.
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Characterizing the Spatial Distribution of Dendritic RNA at Single Molecule Resolution

Jihoon Kim, Jean G. Rosario, Eric Mendoza, D. Kuang, Junhyong Kim   +4 more
openalex   +1 more source

IRIS: A Machine Learning-Based Pose Reranking Tool for RNA-Ligand Docking. [PDF]

ACS Omega
Amburn JA, J Rukmani S, Parks JM, Smith JC.   +3 more
europepmc   +1 more source