Results 291 to 300 of about 5,194,805 (386)
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
In silico screening and experimental validation identify riboflavin as an RNA-targeted antiviral against SARS-CoV-2. [PDF]
Jeong CH+5 more
europepmc +1 more source
RNA Synthesis and Degradation during Antibiotic Treatment and its Relation to Antibiotic-induced Lag
T. D. Brock, Melissa L. Brock
openalex +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian+6 more
wiley +1 more source
4D structural biology-quantitative dynamics in the eukaryotic RNA exosome complex. [PDF]
Liebau J+6 more
europepmc +1 more source
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
RNA modification is the mark and strategy for host-microbe interactions. [PDF]
Tian Y, Wang X.
europepmc +1 more source
Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
S. Diebold+4 more
semanticscholar +1 more source
Fervidibacter sacchari is a member of the bacterial phylum Armatimonadota, only a few of which have been cultivated. It is a hyperthermophilic polysaccharide degradation specialist. We show that a secreted enzyme, Fsa02490Xyn, is an endoxylanase belonging to glycoside hydrolase family 10.
Nicole Torosian+10 more
wiley +1 more source