Tissue-specific RNA surveillance? Nonsense-mediated mRNA decay causes collagen X haploinsufficiency in Schmid metaphyseal chondrodysplasia cartilage [PDF]
, 2003 John F. Bateman
openalex +1 more source
Advanced Materials Technologies, EarlyView.Thermal annealing improves the structure, stiffness, and piezoelectric properties of poly(vinylidene flouride‐trifluoroethylene) (PVDF‐TrFE) nanofiber scaffolds. These annealed scaffolds promote Schwann cell proliferation and matrix remodeling in vitro and demonstrate in vivo biocompatibility.
Maksym Krutko +12 more
wiley +1 more source
PELOTA and HBS1 suppress co-translational messenger RNA decay in Arabidopsis. [PDF]
Plant Direct, 2023 Guo R, Gregory BD.
europepmc +1 more source
A Hox gene mutation that triggers nonsense-mediated RNA decay and affects alternative splicing during Drosophila development [PDF]
, 2003 Claudio R. Alonso
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Transcript Identification Using Arrayed Hydrogels With TrapFISH
Advanced Materials Technologies, EarlyView.TrapFISH is a novel method for high‐throughput single‐cell transcriptomics. It embeds cells in hyaluronic acid hydrogel beads and uses probe hybridization to quantify custom gene panels. By arraying hydrogels in microfluidic devices, cell barcoding is removed, enhancing scalability for studying cellular heterogeneity and rare cell states by targeting ...
David B. Morse +5 more
wiley +1 more source
Nanomaterial‐Based Optical Biosensors for SARS‐CoV‐2 Detection: A Retrospective of the Pandemic
Advanced Sensor Research, EarlyView.This review discusses nanomaterial‐based optical biosensors developed for or adapted to the detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). It concludes by providing a perspective on how lessons learned during the coronavirus disease of 2019 (COVID‐19) pandemic may be applied for future research on nanomaterial‐based ...
Flavie Martin +2 more
wiley +1 more source
Circadian Control of Messenger RNA Stability. Association with a Sequence-Specific Messenger RNA Decay Pathway [PDF]
, 2005 Preetmoninder Lidder +4 more
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m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade [PDF]
, 2019 Melanoma is one of the most deadly and therapy-resistant cancers. Here we show that N6-methyladenosine (m6A) mRNA demethylation by fat mass and obesity-associated protein (FTO) increases melanoma growth and decreases response to anti-PD-1 blockade ...
Aplin, Andrew E. +10 more
core +1 more source
Digital Bioassays on the Slipchip Microfluidic Devices
Advanced Sensor Research, EarlyView.This review summarizes recent advances in SlipChip‐based digital bioassays, highlighting their simple “load and slip” operation for fluid partitioning which eliminate the need for sophisticated fluidic systems. Applications include digital nucleic acid analysis, digital protein analysis and single‐cell analysis, demonstrating the platform‘s potential ...
Qingqing Luo +5 more
wiley +1 more source
Upf1, an RNA Helicase Required for Nonsense-Mediated mRNA Decay, Modulates the Transcriptional Response to Oxidative Stress in Fission Yeast [PDF]
, 2006 M. Gabriel +3 more
openalex +1 more source