Results 151 to 160 of about 208,041 (335)
Advanced Sensor Research, EarlyView.A deployable, chip‐integrated approach to the detection of heart attack biomarkers is demonstrated using silicon photonic microring resonators combined with microfluidics. By applying the Pound–Drever–Hall frequency locking technique, sensor signals are measured with improved signal‐to‐noise ratio, applying this to real‐time, selective readouts.
Evan Diamandikos +9 more
wiley +1 more source
The long and short of EJC-independent nonsense-mediated RNA decay. [PDF]
Biochem Soc Trans, 2023 Muñoz O, Lore M, Jagannathan S.
europepmc +1 more source
Asymptomatic Isolated Human Glycerol Kinase Deficiency Associated with Splice-Site Mutations and Nonsense-Mediated Decay of Mutant RNA [PDF]
, 2006 Yao-Hua Zhang +5 more
openalex +1 more source
Advanced Sensor Research, EarlyView.This perspective discusses the charge transfer mechanism in single‐atom/small‐cluster SERS systems supported by semiconducting and metallic substrates. Integrating single‐atom/small‐cluster SERS with photocatalytic processes offers unprecedented opportunities for real‐time plasmon‐free reaction monitoring.
Ruinan Wang +7 more
wiley +1 more source
Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD
Advanced Science, EarlyView.TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang +9 more
wiley +1 more source
Characterization of the role of ribonucleases in Salmonella small RNA decay [PDF]
, 2007 Sandra C. Viegas +5 more
openalex +1 more source
Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice
Advanced Science, EarlyView.Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia +29 more
wiley +1 more source
Mutational analysis of a viral RNA element that counteracts rapid RNA decay by interaction with the polyadenylate tail [PDF]
, 2007 Nicholas K. Conrad +3 more
openalex +1 more source
Advanced Science, EarlyView.WSGC peptide reverses drug resistance in GA by modulating the Notch signaling pathway and mitophagy at the molecular level. Abstract This study investigates the molecular mechanisms by which superparamagnetic iron oxide nanoparticles (SPIONs) loaded with the WSGC peptide (WSGC@FA@PEG/PEI‐SPIONs)—a 40‐amino acid polypeptide derived from apoC‐III ...
Dongjian Song +10 more
wiley +1 more source
Roles for TbDSS-1 in RNA surveillance and decay of maturation by-products from the 12S rRNA locus [PDF]
, 2007 Jonelle L. Mattiacio, Laurie K. Read
openalex +1 more source