This study demonstrates a label‐free optical method to monitor cells using a terahertz metasurface‐based biosensing platform. The obtained terahertz signal change for the cell‐contained nanoslots before and after external stimulus is analyzed in terms of transmittance and frequency shift, dynamically representing the cell apoptosis process.
Yeeun Roh+4 more
wiley +1 more source
Amentoflavone from Selaginella tamariscina inhibits SARS-CoV-2 RNA-dependent RNA polymerase
The SARS-CoV-2 pandemic caused millions of deaths due to its prominent infectivity and mortality. Although the vaccines and medicines for SARS-CoV-2 are on the market, new coronavirus variants like influenza are expected to reemerge continuously ...
Kyoung Won Youn+7 more
doaj
Studies on the Conformation of DNA‐Dependent RNA Polymerase in Solution by Small‐Angle X‐Ray Measurements [PDF]
Ingrid Pilz, O. Kratky, Dietmar Rabussay
openalex +1 more source
An RNA condensate model for the origin of life [PDF]
The RNA World hypothesis predicts that self-replicating RNAs evolved before DNA genomes and coded proteins. Despite widespread support for the RNA World, self-replicating RNAs have yet to be identified in a natural context, leaving a key 'missing link' for this explanation of the origin of life.
arxiv
Functional Molecule‐Integrated Nano‐Interfaces for Detection of Extracellular Vesicles
Functional molecule‐integrated nano‐interfaces for detection of extracellular vesicles prepared via template polymerization using multifunctional polymer–silica nanoparticle complex as a template followed by post‐functionalization modification are demonstrated.
Hirobumi Sunayama+2 more
wiley +1 more source
Current understanding of nucleoside analogs inhibiting the SARS-CoV-2 RNA-dependent RNA polymerase. [PDF]
Xu T, Zhang L.
europepmc +1 more source
Template Specificity of Eucaryotic DNA‐Dependent RNA Polymerases [PDF]
Sarah Jane Flint+3 more
openalex +1 more source
FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang+14 more
wiley +1 more source
The Functional Implications of Broad Spectrum Bioactive Compounds Targeting RNA-Dependent RNA Polymerase (RdRp) in the Context of the COVID-19 Pandemic. [PDF]
Comunale BA+5 more
europepmc +1 more source
On the Initiation of Transcription by DNA‐Dependent RNA Polymerase from Escherichia coli [PDF]
Rolf Schäfer+3 more
openalex +1 more source