Inhalable Hsa‐miR‐30a‐3p Liposomes Attenuate Pulmonary Fibrosis
The study explores inhalable hsa‐miR‐30a‐3p‐loaded liposomes as a treatment for bleomycin‐induced pulmonary fibrosis in mice. Hsa‐miR‐30a‐3p is electroporated into liposomes and formulated into a dry powder for inhalation. Delivered via dry powder inhalation, it improves pulmonary function, promotes myofibroblast de‐differentiation by targeting CNPY2 ...
Shuo Liu+14 more
wiley +1 more source
Human super antibody to viral RNA-dependent RNA polymerase produced by a modified Sortase self-cleave-bacteria surface display system. [PDF]
Glab-Ampai K+6 more
europepmc +1 more source
RNA-dependent DNA polymerase activity of RNA tumor virus. VI. Processive mode of action of avian myeloblastosis virus polymerase [PDF]
Jonathan Leis
openalex +1 more source
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang+17 more
wiley +1 more source
RNA Overwriting of Cellular mRNA by Cas13b-Directed RNA-Dependent RNA Polymerase of Influenza A Virus. [PDF]
Ogasawara S, Ebashi S.
europepmc +1 more source
Affinity Chromatography of RNA-Dependent DNA Polymerase from RNA Tumor Viruses on a Solid Phase Immunoadsorbent [PDF]
David M. Livingston+3 more
openalex +1 more source
Chromatin Organization Governs Transcriptional Response and Plasticity of Cancer Stem Cells
Through a combination of transcriptomic and histone mapping studies integrated with chromatin imaging, we define how chromatin organization in nanoscale packing domains fine tunes the plasticity of cancer stem cells (CSCs) driving evasion from and survival after chemotherapy.
Yinu Wang+20 more
wiley +1 more source
Covalent Inhibitors from Saudi Medicinal Plants Target RNA-Dependent RNA Polymerase (RdRp) of SARS-CoV-2. [PDF]
Bakheit AH+5 more
europepmc +1 more source
Distinct molecular structures of nuclear class I, II, and III DNA-dependent RNA polymerases.
Virgil E. F. Sklar+2 more
openalex +1 more source