Results 181 to 190 of about 509,868 (288)

Antiviral Efficacy of Lignan Derivatives (-)-Asarinin and Sesamin Against Foot-and-Mouth Disease Virus by Targeting RNA-Dependent RNA Polymerase (3D^pol). [PDF]

Vet Sci
Semkum P, Mana N, Lueangaramkul V, Phetcharat N, Lekcharoensuk P, Theerawatanasirikul S.   +5 more
europepmc   +1 more source

A fungal RNA-dependent RNA polymerase is a novel player in plant infection and cross-kingdom RNA interference. [PDF]

PLoS Pathog, 2023
Cheng AP, Lederer B, Oberkofler L, Huang L, Johnson NR, Platten F, Dunker F, Tisserant C, Weiberg A.   +8 more
europepmc   +1 more source

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

Triethylamine inhibits influenza A virus infection and growth via mechanisms independent of viral neuraminidase and RNA-dependent RNA polymerase. [PDF]

PLoS One
Shoji M, Nakaoka K, Ishikawa M, Kasai Y, Esumi T, Takahashi E, Kido H, Imawaga H, Kuzuhara T.   +8 more
europepmc   +1 more source

Identification of TMEM53 as a novel SADS-CoV restriction factor that targets viral RNA-dependent RNA polymerase. [PDF]

Emerg Microbes Infect, 2023
Yao YL, Luo Y, Wang Q, Wang Q, Geng R, Chen Y, Liu MQ, Li B, Chen J, Wu CG, Jia JK, Luo JY, He YT, Jiang TT, Zhu Y, Hu B, Zhou P, Shi ZL.   +17 more
europepmc   +1 more source

RNA replication by poliovirus RNA-dependent RNA polymerase: effects of residue 5 on elongation complex stability and processivity

, 2007
Sarah E. Hobdey, Peersen, Olve B., Stargell, Laurie, Chen, Chaoping, Wilusz, Carol   +4 more
openalex   +2 more sources

Molecular docking and dynamic simulations study for repurposing of multitarget coumarins against SARS-CoV-2 main protease, papain-like protease and RNA-dependent RNA polymerase

, 2022
Mai E. Shoman, Amer Ali Abd El‐Hafeez, Moteb Khobrani, Abdullah Assiri, Sultan S. Al Thagfan, Eman M. Othman, Ahmed R. N. Ibrahim   +6 more
openalex   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

Improvement in the potency of a N¹-methylpseudouridine-modified self-amplifying RNA through mutations in the RNA-dependent RNA polymerase. [PDF]

J Biol Chem
Quintana V, Caillava J, Byk LA, Mondotte JA, Battini L, Tarte P, Samsa MM, Filomatori CV, Alvarez DE.   +8 more
europepmc   +1 more source

Nucleocytoplasmic shuttling of the West Nile virus RNA ‐dependent RNA polymerase NS5 is critical to infection [PDF]

, 2018
Adam J. López‐Denman, Alice Russo, Kylie M. Wagstaff, Peter A. White, David A. Jans, Jason M. Mackenzie   +5 more
openalex   +1 more source