Results 331 to 340 of about 2,110,017 (419)

BALF editome profiling reveals A-to-I RNA editing associated with severity and complications of <i>Mycoplasma pneumoniae</i> pneumonia in children. [PDF]

mSphere
Jin Y-Y, Guo Y, Xiong S-W, Zhang N, Chen J-H, Liu F.   +5 more
europepmc   +1 more source

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

Advanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao, Yule Yong, Zhaohui Zheng, Kui Zhang, Wei Li, Jiayi Liu, Siyi Zhou, Juan‐juan Qin, Haoyang Sun, Yatao Wang, Xianghui Fu, Xing Luo, Siyu Chen, Zhi‐Gang She, Jingjing Cai, Ping Zhu   +15 more
wiley   +1 more source

TbMP81 is required for RNA editing in Trypanosoma brucei

, 2002
Maciej Drożdż, Setareh S. Palazzo, Reza Salavati, Jeff O'Rear, Christine Clayton, Kenneth Stuart   +5 more
openalex   +2 more sources

Structural perspectives on adenosine to inosine RNA editing by ADARs. [PDF]

Mol Ther Nucleic Acids
Fisher AJ, Beal PA.
europepmc   +1 more source

α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model

Advanced Science, EarlyView.
A novel midbrain–hindbrain assembloid model demonstrates the spread of α‐synuclein pathology, a hallmark of Parkinson's disease, mimicking Braak's hypothesis. This model reveals how pathology propagates from the hindbrain to the midbrain, inducing synaptic changes and early signs of neuronal vulnerability. It offers an innovative platform for exploring
Gemma Gomez‐Giro, Daniela Frangenberg, Daniela Vega, Alise Zagare, Kyriaki Barmpa, Paul M. A. Antony, Graham Robertson, Rahman Sabahi‐Kaviani, Kristian Haendler, Nathalie Kruse, Florentia Papastefanaki, Rebecca Matsas, Malte Spielmann, Regina Luttge, Jens C. Schwamborn   +14 more
wiley   +1 more source

The Pentatricopeptide Repeat Protein OsPPR674 Regulates Rice Growth and Drought Sensitivity by Modulating RNA Editing of the Mitochondrial Transcript <i>ccmC</i>. [PDF]

Int J Mol Sci
Li J, Zhang L, Li C, Chen W, Wang T, Tan L, Qiu Y, Song S, Li B, Li L.   +9 more
europepmc   +1 more source

Inhibition of Aberrant Activated Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis by Leishmania Peptide via the Regulation of Fatty Acid Synthesis Metabolism

Advanced Science, EarlyView.
LACK156‐173 is internalized into RA‐FLSs via CAPN2‐mediated endocytosis and inhibits the aggressive phenotype of RA‐FLSs by restoring dysregulated fatty acid synthesis metabolism mediated by overexpressed FASN. The findings suggest that targeting the restoration of fatty acid metabolism could potentially alleviate synovial invasion and joint damage in ...
Jianling Su, Xuemei Fan, Yaoyao Zou, Guangtao Fu, Shiqi Feng, Xiaoxue Wang, Yongmei Yu, Lin Li, Zhenhua Bian, Rongrong Huang, Linmang Qin, Jiping Chen, Qin Zeng, Kai Yan, Caiyue Gao, Zhexiong Lian, Xin Li, Yang Li   +17 more
wiley   +1 more source

Role of Uridylate-Specific Exoribonuclease Activity in Trypanosoma brucei RNA Editing

, 2002
Robert P. Igo, David S. Weston, Nancy Lewis Ernst, Aswini K. Panigrahi, Reza Salavati, Kenneth Stuart   +5 more
openalex   +1 more source

RNA editing-induced structural and functional adaptations of NAD9 in Triticum aestivum under drought stress. [PDF]

Front Plant Sci
Mohamed NG, Ramadan AM, Amer M, Morsy Y, Mohamed RA, Said OAM, Alnufaei AA, Ibrahim MIM, Hassanein SE, Eissa HF.   +9 more
europepmc   +1 more source

Microbiota‐Derived Inosine Suppresses Systemic Autoimmunity via Restriction of B Cell Differentiation and Migration

Advanced Science, EarlyView.
Lactobacillus johnsonii and its associated purine metabolite inosine not only restrict systemic B cell differentiation, but also contribute to immune cell infiltration in the kidneys, thereby serving dual functions in mitigating the progression of systemic lupus erythematosus (SLE).
Lingyu Gao, Yuhan Zhang, Zhi Hu, Shengwen Chen, Qiaolin Wang, Yong Zeng, Huiqi Yin, Junpeng Zhao, Yijing Zhan, Changxing Gao, Yue Xin, Bing Chen, Stijn van der Veen, Ming Zhao, Deyu Fang, Qianjin Lu   +15 more
wiley   +1 more source