Results 211 to 220 of about 99,329 (307)

Epigenetic Aging in Brain Tissue of the Self‐Fertilizing Vertebrate, Kryptolebias marmoratus

Ecology and Evolution, Volume 16, Issue 6, June 2026.
Using the self‐fertilizing vertebrate Kryptolebias marmoratus, we developed an epigenetic clock from brain tissue that predicts chronological age with high accuracy, demonstrating that DNA methylation changes consistently with age even in the near absence of genetic variation. The 40 age‐associated CpG sites identified map to genes with conserved roles
Justine Bélik, Frédéric Silvestre
wiley   +1 more source

The host RNA helicase DDX6 restricts avian influenza virus replication by targeting viral NP and modulating ISG15. [PDF]

Poult Sci
Lu X, Lu C, He M, Tang X, Ji Z, Wu H, Liu K, Yang W, Chen Y, Gao R, Hu J, Gu M, Hu S, Liu X, Wang X, Liu X.   +15 more
europepmc   +1 more source

Dissecting the Interaction Domains of SARS-CoV-2 Nucleocapsid Protein and Human RNA Helicase DDX3X and Search for Potential Inhibitors. [PDF]

Int J Mol Sci
Lodola C, Pallotta MM, Manetti F, Governa P, Crespan E, Maga G, Secchi M.   +6 more
europepmc   +1 more source

AMPK modulates a DEAH box RNA-helicase to attenuate TOR signaling and establish developmental quiescence in Caenorhabditis elegans. [PDF]

PLoS Biol
Rashid S, Roy R.
europepmc   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

The DEAD-box RNA helicase eIF4A is a crucial factor for stem-cell activity and reproduction of the parasite <i>Schistosoma mansoni</i>. [PDF]

Front Cell Infect Microbiol
Welsch S, Puckelwaldt O, Ajmera S, Magari F, Haeberlein S, Grünweller A, Grevelding CG.   +6 more
europepmc   +1 more source

The Effect of Protein Tagging on Aggregation and Phase Separation

Journal of Cellular Biochemistry, Volume 127, Issue 6, June 2026.
ABSTRACT Protein tags are widely used for purification, solubilization, detection, and imaging, yet they can substantially alter protein self‐assembly. This interference is particularly significant for intrinsically disordered proteins and low‐complexity domains, whose aggregation and phase separation are mediated by weak multivalent interactions that ...
Harunobu Saito, Kenji Sugase
wiley   +1 more source

In vitro characterization of the yeast DEAH/RHA RNA helicase Dhr1. [PDF]

J Biol Chem
Lin R, Elmir E, Reynolds MJ, Johnson AW.
europepmc   +1 more source

Genomic and Transcriptomic Insights Into Salinity Tolerance in Dry Pea

Legume Science, Volume 8, Issue 2, June 2026.
ABSTRACT Salinity is a major crop production constraint in dry pea (Pisum sativum L.), making the development of salt‐tolerant varieties essential to improve crop productivity and land‐use efficiency. The genetic mechanisms of salt tolerance in dry pea are largely unknown, and research on salt‐tolerant genes is limited.
Shailesh Raj Acharya, Emmanuella Bredu, Harry Navasca, Hannah Worral, Lisa Piche, Rica Amor Saludares, Josephine Princy Johnson, Clarice Coyne, Kevin McPhee, Qi Zhang, Michael Ostlie, Nonoy Bandillo   +11 more
wiley   +1 more source

The RNA helicase HrpA rescues collided ribosomes in E. coli. [PDF]

Mol Cell
Campbell A, Esser HF, Burroughs AM, Berninghausen O, Aravind L, Becker T, Green R, Beckmann R, Buskirk AR.   +8 more
europepmc   +1 more source