Results 171 to 180 of about 125,618 (325)
A Role for the TFIIH XPB DNA Helicase in Promoter Escape by RNA Polymerase II [PDF]
, 1999 Rodney J. Moreland +5 more
openalex +1 more source
Membraneless Organelles and Phase Separation in Tumours: Mechanisms and Prospects
Cell Proliferation, EarlyView.The Salient and Novel Findings: This article summarises the latest research advancements in phase separation within tumours, with a particular focus on the role and molecular mechanisms of liquid–liquid phase separation (LLPS) in tumour progression.
Hao Yang +3 more
wiley +1 more source
A Nucleolar RNA Helicase Recognized by Autoimmune Antibodies from a Patient With Watermelon Stomach Disease [PDF]
, 1996 Benigno C. Valdez +7 more
openalex +1 more source
Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop [PDF]
, 2017 DEAD-box proteins disrupt or remodel RNA and protein/RNA complexes at the expense of ATP. The catalytic core is composed of two flexibly connected RecA-like domains.
Diederichsen, Ulf +4 more
core
The FEBS Journal, EarlyView.TDP‐43 protein plays a pathological role in sporadic and familial amyotrophic lateral sclerosis (ALS). Here, we developed a cellular model overexpressing TDP‐43 with three mutations linked to familial ALS, termed ‘3X‐TDP‐43’. Mutant 3X‐TDP‐43 expression showed deficits in autophagy flux and colocalization with stress granules.
Matthew B. Dopler +20 more
wiley +1 more source
RNA helicase: a novel activity associated with a protein encoded by a positive strand RNA virus
, 1990 Sonia Laı́n +2 more
openalex +1 more source
A Novel Gonadotropin-regulated Testicular RNA Helicase [PDF]
, 1999 Pei‐Zhong Tang +2 more
openalex +1 more source
Epigenetic control of cell identities from epiblast to gastrulation
The FEBS Journal, EarlyView.In this review, we present and contextualize current knowledge about the roles of epigenetic modifiers during the development of mouse epiblast to gastrulation stage. The epigenetic regulation of enhancer and promoter elements by DNA methylation, histone modifications, and chromatin accessibility in concert with lineage‐specific transcription factors ...
Katrin M. Schüle, Simone Probst
wiley +1 more source
The FEBS Journal, EarlyView.Under normoxic conditions, the SUMOylated fraction of TFAP2A cannot interact with the Ku70/Ku80 complex, nor it can bind to chromatin. The unSUMOylated fraction pre‐occupies the chromatin of a subset of hypoxia‐induced genes together with the Ku70/Ku80 complex for basal euchromatin formation. Under hypoxic conditions, the SUMOylation equilibrium shifts
Amalia Kanoura +8 more
wiley +1 more source