The advances of DEAD-box RNA helicase 17 in chronic non-infectious diseases. [PDF]
Xiong M +8 more
europepmc +1 more source
The newly discovered Q motif of DEAD‐box RNA helicases regulates RNA‐binding and helicase activity [PDF]
Olivier Cordin +4 more
openalex +1 more source
The Double Face of Base Excision Repair: Preventing and Triggering Double‐Strand Breaks
Base excision repair is conserved from bacteria to man, robustly eliminating oxidized bases in DNA and reinserting the appropriate nucleotide to restore an intact double helix. Recent results describe conditions and mechanisms that misregulate long‐patch BER to generate double‐strand breaks, triggering chromosome fragmentation and cell death, altering ...
Susan M. Gasser
wiley +1 more source
The conserved SEN1 DNA/RNA helicase has multiple functions during yeast meiosis. [PDF]
Gaglione R +6 more
europepmc +1 more source
Crystal structures of the DExH-box RNA helicase DHX9. [PDF]
Lee YT +4 more
europepmc +1 more source
A 5′-Flanking Region of Gonadotropin-Regulated Testicular RNA Helicase (GRTH/DDX25) Gene Directs Its Cell-Specific Androgen-Regulated Gene Expression in Testicular Germ Cells [PDF]
Raghuveer Kavarthapu +4 more
openalex +1 more source
Engineering of High‐Yield Recombinant Adeno‐Associated Virus Producer Plasmids
Graphical Abstract and Lay Summary Recombinant adeno‐associated viruses (AAV) are important in gene therapy but their production may be impaired by non‐optimized gene design. In this study, the authors demonstrate that production was best when the AAV replicase gene was in a wild‐type configuration while the complexity of other genetic elements could ...
Marco T. Radukic +10 more
wiley +1 more source
Unwinding new therapeutic opportunities in rhabdomyosarcoma: the role of RNA helicase DDX5. [PDF]
Bianconi V, Mozzetta C.
europepmc +1 more source
Application of synthetic lethality screening in drug resistance models. Abstract Background and Rationale Synthetic lethality (SL)‐based strategies hold significant promise for overcoming therapeutic resistance, a critical bottleneck in cancer treatment where cancer cells evade anticancer therapies, leading to diminished efficacy or treatment failure ...
Junyan Li +4 more
wiley +1 more source
Dual roles of DEAD-box RNA helicase Brr2 in genome stability regulation. [PDF]
Chen X +9 more
europepmc +1 more source

