Results 171 to 180 of about 92,282 (271)

The advances of DEAD-box RNA helicase 17 in chronic non-infectious diseases. [PDF]

open access: yesFront Cardiovasc Med
Xiong M   +8 more
europepmc   +1 more source

The newly discovered Q motif of DEAD‐box RNA helicases regulates RNA‐binding and helicase activity [PDF]

open access: bronze, 2004
Olivier Cordin   +4 more
openalex   +1 more source

The Double Face of Base Excision Repair: Preventing and Triggering Double‐Strand Breaks

open access: yesBioEssays, Volume 48, Issue 1, January 2026.
Base excision repair is conserved from bacteria to man, robustly eliminating oxidized bases in DNA and reinserting the appropriate nucleotide to restore an intact double helix. Recent results describe conditions and mechanisms that misregulate long‐patch BER to generate double‐strand breaks, triggering chromosome fragmentation and cell death, altering ...
Susan M. Gasser
wiley   +1 more source

The conserved SEN1 DNA/RNA helicase has multiple functions during yeast meiosis. [PDF]

open access: yesPLoS Genet
Gaglione R   +6 more
europepmc   +1 more source

Crystal structures of the DExH-box RNA helicase DHX9. [PDF]

open access: yesActa Crystallogr D Struct Biol, 2023
Lee YT   +4 more
europepmc   +1 more source

Engineering of High‐Yield Recombinant Adeno‐Associated Virus Producer Plasmids

open access: yesBiotechnology Journal, Volume 21, Issue 1, January 2026.
Graphical Abstract and Lay Summary Recombinant adeno‐associated viruses (AAV) are important in gene therapy but their production may be impaired by non‐optimized gene design. In this study, the authors demonstrate that production was best when the AAV replicase gene was in a wild‐type configuration while the complexity of other genetic elements could ...
Marco T. Radukic   +10 more
wiley   +1 more source

Synthetic lethality in cancer therapy: Mechanisms, models and clinical translation for overcoming therapeutic resistance

open access: yesClinical and Translational Medicine, Volume 16, Issue 1, January 2026.
Application of synthetic lethality screening in drug resistance models. Abstract Background and Rationale Synthetic lethality (SL)‐based strategies hold significant promise for overcoming therapeutic resistance, a critical bottleneck in cancer treatment where cancer cells evade anticancer therapies, leading to diminished efficacy or treatment failure ...
Junyan Li   +4 more
wiley   +1 more source

Dual roles of DEAD-box RNA helicase Brr2 in genome stability regulation. [PDF]

open access: yesNat Commun
Chen X   +9 more
europepmc   +1 more source

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