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Plant RNA helicases: linking aberrant and silencing RNA
Trends in Plant Science, 2009RNA helicases are ATPases that are capable of rearranging RNA and ribonucleoprotein (RNP) structure, and they can potentially function in any aspect of RNA metabolism. The RNA helicase gene family of plant genomes is larger and more diverse than genome families observed in other systems and provides an ideal model for investigation of the physiological
Linder, Patrick, Owttrim, George
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Helicases and RNA unwinding in translation
Current Opinion in Structural Biology, 1993Abstract RNA helicases melt regions of duplex RNA in a process that requires energy derived from the hydrolysis of nucleoside triphosphates. The process of protein synthesis in prokaryotes and eukaryotes involves one proven RNA helicase (elF-4A) and several putative RNA helicases.
Nahum Sonenberg, Arnim Pause
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RNA helicase A is necessary for translation of selected messenger RNAs
Nature Structural & Molecular Biology, 2006RNA helicase A (RHA) is a highly conserved DEAD-box protein that activates transcription, modulates RNA splicing and binds the nuclear pore complex. The life cycle of typical mRNA involves RNA processing and translation after ribosome scanning of a relatively unstructured 5' untranslated region (UTR).
Daniel R. Schoenberg +5 more
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Analysis of Cofactor Effects on RNA Helicases
2012RNA helicases are involved in all aspects of RNA metabolism. Since the helicase core is conserved between all helicases, specificity for particular cellular roles must arise from interactions with specific cofactors, which can regulate RNA binding and enzymatic activity.
Crystal L. Young, Katrin Karbstein
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