Results 21 to 30 of about 1,353,045 (362)

High-throughput sequencing reveals circular substrates for an archaeal RNA ligase. [PDF]

RNA Biol, 2017
Becker HF, Héliou A, Djaout K, Lestini R, Regnier M, Myllykallio H.   +5 more
europepmc   +2 more sources

Archaeal RNA ligase from thermoccocus kodakarensis for template dependent ligation. [PDF]

RNA Biol, 2017
Zhang L, Tripathi A.
europepmc   +2 more sources

Structure and Mechanism of RNA Ligase

Structure, 2004
T4 RNA ligase 2 (Rnl2) exemplifies an RNA ligase family that includes the RNA editing ligases (RELs) of Trypanosoma and Leishmania. The Rnl2/REL enzymes are defined by essential signature residues and a unique C-terminal domain, which we show is essential for sealing of 3'-OH and 5'-PO4 RNA ends by Rnl2, but not for ligase adenylation or phosphodiester
C HO, L WANG, Christopher D. Lima, S SHUMAN   +3 more
  +6 more sources

Reactions at the termini of tRNA with T4 RNA ligase.

Nucleic Acids Research, 1978
T4 RNA ligase will catalyze the addition of nucleoside 3', 5'-bisphosphates onto the 3' terminus of tRNA resulting in tRNA molecule one nucleotide longer with a 3' terminal phosphate. Under appropriate conditions the reaction is quantitative and, if high
A. Bruce, O. Uhlenbeck
semanticscholar   +5 more sources

Insights into the structure and function of the RNA ligase RtcB. [PDF]

Cell Mol Life Sci, 2023
AbstractTo be functional, some RNAs require a processing step involving splicing events. Each splicing event necessitates an RNA ligation step. RNA ligation is a process that can be achieved with various intermediaries such as self-catalysing RNAs, 5′–3′ and 3′–5′ RNA ligases.
Moncan M, Rakhsh-Khorshid H, Eriksson LA, Samali A, Gorman AM.   +4 more
europepmc   +3 more sources

Putative RNA Ligase RtcB Affects the Switch between T6SS and T3SS in Pseudomonas aeruginosa. [PDF]

Int J Mol Sci, 2021
Dadashi M, Chen L, Nasimian A, Ghavami S, Duan K.   +4 more
europepmc   +3 more sources

HIV-1 vif mediates ubiquitination of the proximal protomer in the APOBEC3H dimer to induce degradation [PDF]

Nature Communications
The APOBEC3 family of cytidine deaminases restricts retroviruses like HIV-1 by mutating viral DNA. HIV-1 evades this restriction by producing Vif, which recruits the Cullin-5 (CUL5) E3 ubiquitin ligase complex to promote APOBEC3 degradation.
Katarzyna A. Skorupka, Kazuhiro Matsuoka, Bakar Hassan, Rodolfo Ghirlando, Vanivilasini Balachandran, Ting-Hua Chen, Kylie J. Walters, Celia A. Schiffer, Matthias Wolf, Yasumasa Iwatani, Hiroshi Matsuo   +10 more
doaj   +2 more sources

RtcB Is the RNA Ligase Component of an Escherichia coli RNA Repair Operon* [PDF]

Journal of Biological Chemistry, 2011
RNA 2′,3′-cyclic phosphate ends play important roles in RNA metabolism as substrates for RNA ligases during tRNA restriction-repair and tRNA splicing.
N. Tanaka, S. Shuman
semanticscholar   +4 more sources

An RNA Ligase from Deinococcus radiodurans [PDF]

Journal of Biological Chemistry, 2004
Although DNA repair pathways have been the focus of much attention, there is an emerging appreciation that distinct pathways exist to maintain or manipulate RNA structure in response to breakage events. Here we identify an RNA ligase (DraRnl) from the radiation-resistant bacterium Deinococcus radiodurans. DraRnl seals 3'-OH/5'-PO4 RNA nicks in either a
Alexandra Martins, Stewart Shuman
openalex   +5 more sources

Cross-Catalytic Replication of an RNA Ligase Ribozyme [PDF]

Chemistry & Biology, 2004
A self-replicating RNA ligase ribozyme was converted to a cross-catalytic format whereby two ribozymes direct each other's synthesis from a total of four component substrates. Each ribozyme binds two RNA substrates and catalyzes their ligation to form the opposing ribozyme.
Dong‐Eun Kim, Gerald F. Joyce
openalex   +5 more sources