Characterization of a novel eukaryal nick-sealing RNA ligase from Naegleria gruberi. [PDF]
RNA, 2015 The proteome of the amoebo-flagellate protozoan Naegleria gruberi is rich in candidate RNA repair enzymes, including 15 putative RNA ligases, one of which, NgrRnl, is a eukaryal homolog of Deinococcus radiodurans RNA ligase, DraRnl.
Unciuleac MC, Shuman S.
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Insights into the structure and function of the RNA ligase RtcB. [PDF]
Cell Mol Life Sci, 2023 Moncan M +4 more
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RtcB, a Novel RNA Ligase, Can Catalyze tRNA Splicing and HAC1 mRNA Splicing in Vivo [PDF]
Journal of Biological Chemistry, 2011 RtcB enzymes are novel RNA ligases that join 2′,3′-cyclic phosphate and 5′-OH ends. The phylogenetic distribution of RtcB points to its candidacy as a tRNA splicing/repair enzyme.
Naoko Tanaka +2 more
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Putative RNA Ligase RtcB Affects the Switch between T6SS and T3SS in Pseudomonas aeruginosa. [PDF]
Int J Mol Sci, 2021 Dadashi M +4 more
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Archaeal RNA ligase from thermoccocus kodakarensis for template dependent ligation. [PDF]
RNA Biol, 2017 Zhang L, Tripathi A.
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Making ends meet: a role of
EMBO Journal, 2014 Witold Filipowicz
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The RtcB RNA ligase is an essential component of the metazoan unfolded protein response. [PDF]
EMBO Rep, 2014 Kosmaczewski SG +8 more
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Life, 2022 The acquisition of functions via the elongation of nucleotides is an important factor in the development of the RNA world. In our previous study, we found that the introduction of complementary seven-membered kissing loops into inactive R3C ligase ...
Hiromi Mutsuro-Aoki, Koji Tamura
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Mutational analysis of Trypanosoma brucei RNA editing ligase reveals regions critical for interaction with KREPA2. [PDF]
PLoS ONE, 2015 The Trypanosoma brucei parasite causes the vector-borne disease African sleeping sickness. Mitochondrial mRNAs of T. brucei undergo posttranscriptional RNA editing to make mature, functional mRNAs.
Vaibhav Mehta +3 more
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Molecular Anatomy of the Class I Ligase Ribozyme for Elucidation of the Activity-Generating Unit
Biology, 2023 The class I ligase ribozyme consists of 121 nucleotides and shows a high catalytic rate comparable to that found in natural proteinaceous polymerases. In this study, we aimed to identify the smaller active unit of the class I ligase ribozyme comprising ...
Miho Kasuga +3 more
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