Results 311 to 320 of about 1,353,045 (362)

SUMOylation: Interplaying with the plant disease triangle. [PDF]

PLoS Pathog
Li C, Yang C, Lai J.
europepmc   +1 more source

An m⁶A methyltransferase confers host resistance by degrading viral proteins through ubiquitination. [PDF]

Nat Commun
Guo J, Zhang T, Xie H, Hu H, Shi C, Zhao Y, Yin J, Xu G, Wu Z, Wang P, Liu J, Liu P, Zhong K, Chen F, Chen J, Yang J.   +15 more
europepmc   +1 more source

Structural and biochemical characterization of the 3'-5' tRNA splicing ligases. [PDF]

J Biol Chem
Chamera S, Zajko W, Czarnocki-Cieciura M, Jaciuk M, Koziej Ł, Nowak J, Wycisk K, Sroka M, Chramiec-Głąbik A, Śmietański M, Gołębiowski F, Warmiński M, Jemielity J, Glatt S, Nowotny M.   +14 more
europepmc   +1 more source

Immunoinformatic development of a multiepitope messenger RNA vaccine targeting lipoate protein ligase and dihydrolipoamide dehydrogenase proteins of <i>Mycoplasma bovis</i> in cattle. [PDF]

Vet World
Al-Fetly DR, Alsallami D, Alsultan A.
europepmc   +1 more source

A SUMO E3 ligase promotes long non-coding RNA transcription to regulate small RNA-directed DNA elimination

Salman Shehzada, Tomoko Noto, Julie Saksouk, Kazufumi Mochizuki   +3 more
openalex   +1 more source

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Enzymatic oligoribonucleotide synthesis with T4 RNA ligase.

Biochemistry, 1978
The substrate specificity of T4 RNA ligase has been examined to determine whether the intermolecular reaction is sufficiently general to realize its potential in the enzymatic synthesis of oligoribonucleotides of defined sequence.
T. England, O. Uhlenbeck
semanticscholar   +4 more sources

A Threose Nucleic Acid Enzyme with RNA Ligase Activity.

Journal of the American Chemical Society, 2021
Threose nucleic acid (TNA) has been considered a potential RNA progenitor in evolution due to its chemical simplicity and base pairing property. Catalytic TNA sequences with RNA ligase activities might have facilitated the transition to the RNA world ...
Yao Wang, Yueyao Wang, Dongfan Song, Xin-Lai Sun, Ze Zhang, Xintong Li, Zhe Li, Hanyang Yu   +7 more
semanticscholar   +1 more source

Efficient splinted ligation of synthetic RNA using RNA ligase.

Methods in molecular biology, 2014
RNA ligation allows the creation of large RNA molecules from smaller pieces. This can be useful in a number of contexts: to generate molecules that are larger than can be directly synthesized; to incorporate site-specific changes or RNA modifications within a large RNA in order to facilitate functional and structural studies; to isotopically label ...
M. Stark, S. Rader
semanticscholar   +4 more sources

3′-Terminal labelling of RNA with T4 RNA ligase

Nature, 1978
T4 RNA LIGASE catalyses the formation of an internucleotide phosphodiester bond between an oligonucleotide donor molecule with a 5′-terminal phosphate and an oligonucleotide acceptor molecule with a 3′-terminal hydroxyl1–3. Although the minimal acceptor must be a trinucleoside diphosphate, dinucleoside pyrophosphates and mononucleoside 3′,5 ...
T. England, O. Uhlenbeck
semanticscholar   +4 more sources

RNA Ligases

Current Protocols in Molecular Biology, 2008
AbstractT4 RNA ligase 1 catalyzes the ATP‐dependent covalent joining of single‐stranded 5′‐phosphoryl termini of DNA or RNA to single‐stranded 3′‐hydroxyl termini of DNA or RNA. T4 RNA ligase 2 also catalyzes the joining of a 3′‐hydroxyl terminus of RNA to a 5′‐phosphorylated RNA or DNA; unlike T4 RNA ligase 1, this enzyme prefers double‐stranded ...
Nicole M, Nichols, Stanley, Tabor, Larry A, McReynolds   +2 more
openaire   +2 more sources