Results 181 to 190 of about 835,495 (286)

The tRNA epitranscriptomic landscape and RNA modification enzymes in Vibrio cholerae. [PDF]

PLoS Genet
Hardy L, Marchand V, Bourguignon V, Thuillier Q, Dias C, Krin E, Fruchard L, Yaacov DB, Mazel D, Motorin Y, Baharoglu Z.   +10 more
europepmc   +1 more source

Structure and Thermodynamics of N⁶-Methyladenosine in RNA: A Spring-Loaded Base Modification

, 2015
Caroline Roost, Stephen R. Lynch, Pedro J. Batista, Kun Qu, Howard Y. Chang, Eric T. Kool   +5 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

NSUN-Mediated m5C RNA Modification in Stem Cell Regulation. [PDF]

Cells
Moon J, Lee H, Jang Y, Kim SK.
europepmc   +1 more source

Cfp1 is required for gene expression dependent H3K4me3 and H3K9 acetylation in embryonic stem cells [PDF]

, 2014
Bird, Adrian, Clouaire, Thomas, Webb, Shaun   +2 more
core   +1 more source

Characterizing Rna Modifications in the Mouse Brain Throughout Acute and Chronic Toxoplasma Gondii Infection

Nian‐Zhang Zhang, Xiaoliang Jiang, Xiao‐Xuan Zhang, Meng Wang, Wei Wang, Mingfa Yang, Yang Gao, Huanping Guo   +7 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

RNA modification is the mark and strategy for host-microbe interactions. [PDF]

Cell Mol Life Sci
Tian Y, Wang X.
europepmc   +1 more source

Caspases switch off m⁶A RNA modification pathway to reactivate a ubiquitous human tumor virus [PDF]

, 2020
Kun Zhang, Yucheng Zhang, Yunash Maharjan, Febri Gunawan Sugiokto, Jun Wan, Renfeng Li   +5 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source