Results 311 to 320 of about 753,590 (330)
Advances in the Structural and Functional Understanding of m1A RNA Modification. [PDF]
Acc Chem ResSmoczynski J +4 more
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RNA modification gene WDR4 facilitates tumor progression and immunotherapy resistance in breast cancer. [PDF]
J Adv ResLuo Y +14 more
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Research progress of N1-methyladenosine RNA modification in cancer. [PDF]
Cell Commun SignalLiu Y, Zhang S, Gao X, Ru Y, Gu X, Hu X.
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Quantification of RNA modifications [PDF]
Nature Reviews Genetics, 2021 A new report introduces xPore, a computational method and statistical framework for the analysis of differential RNA modifications from nanopore direct RNA sequencing data.
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British Journal of Cancer, 2023
Currently, more than 170 modifications have been identified on RNA. Among these RNA modifications, various methylations account for two-thirds of total cases and exist on almost all RNAs. Roles of RNA modifications in cancer are garnering increasing interest. The research on m6A RNA methylation in cancer is in full swing at present.
Qiling Tang +17 more
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Currently, more than 170 modifications have been identified on RNA. Among these RNA modifications, various methylations account for two-thirds of total cases and exist on almost all RNAs. Roles of RNA modifications in cancer are garnering increasing interest. The research on m6A RNA methylation in cancer is in full swing at present.
Qiling Tang +17 more
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RNA modification to the rescue!
Cell Host & Microbe, 2021RNA expression of endogenous retroviral elements poses a threat to the genome and to cell function, which may ultimately result in disease. Recently published in Nature, Chelmicki and colleagues (2021) identify m6A mRNA methylation as a form of regulation to defend the cell against these attacks.
Shelley L. Berger, Lacey J. Luense
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Role of RNA modifications in cancer [PDF]
Nature Reviews Cancer, 2020 Specific chemical modifications of biological molecules are an efficient way of regulating molecular function, and a plethora of downstream signalling pathways are influenced by the modification of DNA and proteins. Many of the enzymes responsible for regulating protein and DNA modifications are targets of current cancer therapies.
Isaia Barbieri, Tony Kouzarides
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EcoSal Plus, 2005
Transfer RNA (tRNA) from all organisms on this planet contains modified nucleosides, which are derivatives of the four major nucleosides. tRNA from Escherichia coli/Salmonella enterica contains 31 different modified nucleosides, which are all, except for one (Queuosine[Q]), synthesized on an oligonucleotide ...
Glenn R. Björk, Tord G. Hagervall
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Transfer RNA (tRNA) from all organisms on this planet contains modified nucleosides, which are derivatives of the four major nucleosides. tRNA from Escherichia coli/Salmonella enterica contains 31 different modified nucleosides, which are all, except for one (Queuosine[Q]), synthesized on an oligonucleotide ...
Glenn R. Björk, Tord G. Hagervall
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RNA Modifications in Neurodegenerations
2021Considerable evidence is accumulating about the regulatory function of coding- and non-coding RNAs through chemical modifications on their own nitrogen bases. The mechanisms by which the amount and types of these modifications are built to each type of RNA are yet poorly clarified, although some classes of proteins have been identified as actors able ...
Calzoni, Eleonora +8 more
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