Results 151 to 160 of about 966,777 (273)

Selective Cell‐Repellent 3D Scaffold Platform for Proton Radiobiology

Advanced NanoBiomed Research, EarlyView.
A selective cell‐repellent 3D scaffold platform is developed to minimize unwanted 2D cell populations surrounding engineered cell microenvironments. The approach is based on the combination of Lipidure coatings with two‐photon polymerized scaffolds and enables specific characterization of glioblastoma cells’ response to proton irradiation.
Novinda S. Pertiwi, Qais Akolawala, Rob van den Akker, Anggraeini Puspitasari‐Kokko, Henri H. Versteeg, Araci M. R. Rondon, Angelo Accardo   +6 more
wiley   +1 more source

RNA Nanotechnology for Codelivering High-Payload Nucleoside Analogs to Cancer with a Synergetic Effect. [PDF]

Mol Pharm
Li X, Jin K, Liao YC, Lee WJ, Chen LC, Cheng TC, Ho YS, Guo P.   +7 more
europepmc   +1 more source

Broccoli Fluorets: Split Aptamers as a User-Friendly Fluorescent Toolkit for Dynamic RNA Nanotechnology. [PDF]

Molecules, 2018
Chandler M, Lyalina T, Halman J, Rackley L, Lee L, Dang D, Ke W, Sajja S, Woods S, Acharya S, Baumgarten E, Christopher J, Elshalia E, Hrebien G, Kublank K, Saleh S, Stallings B, Tafere M, Striplin C, Afonin KA.   +19 more
europepmc   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source

Specific Delivery of MiRNA for High Efficient Inhibition of Prostate Cancer by RNA Nanotechnology. [PDF]

Mol Ther
Binzel DW, Shu Y, Li H, Sun M, Zhang Q, Shu D, Guo B, Guo P.   +7 more
europepmc   +1 more source

Conditional Guide RNAs: Programmable Conditional Regulation of CRISPR/Cas Function in Bacterial and Mammalian Cells via Dynamic RNA Nanotechnology. [PDF]

ACS Cent Sci, 2019
Hanewich-Hollatz MH, Chen Z, Hochrein LM, Huang J, Pierce NA.   +4 more
europepmc   +1 more source

Mechanical Signatures of Nucleic Acid Trefoil Knot Topology

Angewandte Chemie, EarlyView.
Single‐stranded DNA can be designed with sequences that self‐thread into topological knots. The exact same sequence can alternatively be turned into an unknotted pseudoknot. The topology of the resulting polymer is determined by applying force with optical tweezers, causing the pseudoknot to resolve but the knot to tighten.
David t.R. Bakker, Micah Yang, Isaac T. S. Li   +2 more
wiley   +1 more source

Advances in nanotechnology

, 2017
In this podcast, Professor Moriarty discusses nanotechnology, and how it has led to a convergence of the traditional sciences. He talks about the commercial applications of nanotechnology such as hard disk technology in laptops, stain free materials and ...
Moriarty, Philip
core  

Targeted Delivery of Potent Chemical Drugs and RNAi to Drug-Resistant Breast Cancer Using RNA-Nanotechnology and RNA-Ligand Displaying Extracellular vesicles. [PDF]

RNA Nanomed
Ho YS, Cheng TC, Guo P.
europepmc   +1 more source

Scalable Separation and Purification of M13‐Bacteriophage‐Derived Particles Containing Artificial Single‐Stranded DNA Produced by Escherichia coli

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Single‐stranded DNA (ssDNA) solutions are promising innovations shaping the future of genetic research and medical therapies. In principle, biotechnological mass production of ssDNA can be achieved using Escherichia coli in a high‐cell density fed‐batch process by secreting phagemid particles derived from the filamentous M13 bacteriophages ...
Nathalie Hafner, Wiebke Winkler, Maximilian N. Honemann, Hendrik Dietz, Dirk Weuster‐Botz   +4 more
wiley   +1 more source