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RNA nanotechnology in synthetic biology
Current Opinion in Biotechnology, 2020We review recent advances in the design and expression of synthetic RNA sequences inside cells, to regulate gene expression and to achieve spatial localization of components. We focus on approaches that exploit the programmability of the secondary and tertiary structure of RNA to build scalable and modular devices that fold spontaneously and have the ...
KIM, JONGMIN, FRANCO, ELISA
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RNA cancer nanomedicine: nanotechnology-mediated RNA therapy
Nanoscale, 2022We review the recent progress in nanotechnology-mediated delivery of therapeutic RNAs that have been employed to evoke tumor suppressing responses for cancer therapy.
Bijan Emiliano Ferdows +5 more
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RNA nanotechnology: A new chapter in targeted therapy
Colloids and Surfaces B: Biointerfaces, 2023Nanoparticles have been widely studied in the fields of biotechnology, pharmacy, optics and medicine and have broad application prospects. Numerous studies have shown significant interest in utilizing nanoparticles for chemically coating or coupling drugs, aiming to address the challenges of drug delivery, including degradability and uncertainty ...
Tongtong Lv +6 more
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RNA nanotechnology—The knots and folds of RNA nanoparticle engineering
MRS Bulletin, 2017Abstract
Weizmann, Yossi, Andersen, Ebbe Sloth
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RNAComposer and RNA 3D Structure Prediction for Nanotechnology
Methods, 2016RNAs adopt specific, stable tertiary architectures to perform their activities. Knowledge of RNA tertiary structure is fundamental to understand RNA functions beginning with transcription and ending with turnover. Contrary to advanced RNA secondary structure prediction algorithms, which allow good accuracy when experimental data are integrated into the
Marcin Biesiada +2 more
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RNA Study Using DNA Nanotechnology
2016Transcription is one of the fundamental steps of gene expression, where RNA polymerases (RNAPs) bind to their template genes and make RNAs. In addition to RNAP and the template gene, many molecules such as transcription factors are involved. The interaction and the effect of these factors depend on the geometry.
Hisashi, Tadakuma +2 more
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Micro and nanotechnological tools for study of RNA
Biochimie, 2012Micro and nanotechnologies have originally contributed to engineering, especially in electronics. These technologies enable fabrication and assembly of materials at micrometer and nanometer scales and the manipulation of nano-objects. The power of these technologies has now been exploited in analyzes of biologically relevant molecules.
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RNA Nanotechnology and Therapeutics
2013Section I Introduction: Principles and Fundamentals of RNA Nanotechnology The Emerging Field of RNA Nanotechnology Peixuan Guo Uniqueness, Advantages, Challenges, Solutions, and Perspectives in Therapeutics Applying RNA Nanotechnology Peixuan Guo, Farzin Haque, Brent Hallahan, Randall Reif, Hui Li, and Shaoying Wang Section II RNA Folding, Structure ...
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Budding Alliance of Nanotechnology in RNA Interference Therapeutics
Current Pharmaceutical Design, 2018RNA interference (RNAi), as a novel technique in which RNA molecules limit or silence the gene expression, is currently a hot research topic for producing novel therapeutic materials for challenging diseases. In the development of RNAi-based therapies, nanoscale particles, with a varying diameter along with facile modification methods that can ...
Akshant, Kumawat +6 more
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DNA Nanotechnology as Reference for RNA Nanotechnology
2013Zhen-Gang Wang, Baoquan Ding
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