Results 11 to 20 of about 829,079 (264)
RNA Biology, 2022 Transcriptional pausing occurs across the bacterial genome but the importance of this mechanism is still poorly understood. Only few pauses were observed during the previous decades, leaving an important gap in understanding transcription mechanisms ...
Simon Jeanneau +2 more
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St. Petersburg Polytechnical University Journal: Physics and Mathematics, 2022 This work presents the results of single-molecular studies of the effect of magnesium ions on the dynamic characteristics of transcription elongation of bacterial RNA polymerase.
Arseniev Anatolii +6 more
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Gene Transcription as a Limiting Factor in Protein Production and Cell Growth
G3: Genes, Genomes, Genetics, 2020 Cell growth is driven by the synthesis of proteins, genes, and other cellular components. Defining processes that limit biosynthesis rates is fundamental for understanding the determinants of cell physiology.
Eyal Metzl-Raz +3 more
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Contractions of the C-Terminal Domain of Saccharomyces cerevisiae Rpb1p Are Mediated by Rad5p
G3: Genes, Genomes, Genetics, 2020 The C-terminal domain (CTD) is an essential domain of the largest subunit of RNA polymerase II, Rpb1p, and is composed of 26 tandem repeats of a seven-amino acid sequence, YSPTSPS.
Taylor Stewart +3 more
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Current Opinion in Structural Biology, 2009 The recently solved X-ray crystal structures of archaeal RNA polymerase (RNAP) allow a structural comparison of the transcription machinery among all three domains of life. Archaeal transcription is very simple and all components, including the structures of general transcription factors and RNAP, are highly conserved in eukaryotes. Therefore, it could
Akira, Hirata, Katsuhiko S, Murakami
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Single-peptide DNA-dependent RNA polymerase homologous to multi-subunit RNA polymerase
Nature Communications, 2017 Although all known RNA polymerases have multiple subunits, unrelated single-subunit polymerases have also been described. Here, the authors describe a single-subunit RNA polymerase from the SPβ prophage ofBacillus subtilis, which shares homology to multi-
David Forrest +3 more
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RNA Polymerase-Promoter Interactions: the Comings and Goings of RNA Polymerase [PDF]
Journal of Bacteriology, 1998 Initiation of transcription is a complicated process involving several different phases: promoter location by RNA polymerase, formation of a competent initiation complex, synthesis of the initial phosphodiester bonds, and movement of RNA polymerase from the promoter as it enters the elongation ...
P L, deHaseth +2 more
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Regulation of Eukaryotic RNAPs Activities by Phosphorylation
Frontiers in Molecular Biosciences, 2021 Evolutionarily conserved kinases and phosphatases regulate RNA polymerase II (RNAPII) transcript synthesis by modifying the phosphorylation status of the carboxyl-terminal domain (CTD) of Rpb1, the largest subunit of RNAPII.
Araceli González-Jiménez +5 more
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RNA Polymerase III, Ageing and Longevity
Frontiers in Genetics, 2021 Transcription in eukaryotic cells is performed by three RNA polymerases. RNA polymerase I synthesises most rRNAs, whilst RNA polymerase II transcribes all mRNAs and many non-coding RNAs. The largest of the three polymerases is RNA polymerase III (Pol III)
Yavuz Kulaberoglu +5 more
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Reticulocyte RNA-Dependent RNA Polymerase [PDF]
Proceedings of the National Academy of Sciences, 1973 A cytoplasmic, microsomal bound RNA-dependent RNA polymerase has been purified 2500-fold from rabbit reticulocyte lysates. The synthesis of RNA with the purified enzyme is absolutely dependent on the addition of an RNA template. The best template is hemoglobin messenger RNA, while bacteriophage RNA and poly(A,G) are less active, and DNA is completely ...
K M, Downey +3 more
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