Results 221 to 230 of about 829,079 (264)
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2003
Abstract Bacteriophage T7 RNA polymerase (RNAP) is the best characterized member of a widespread family of RNAPs that includes most bacteriophage-encoded RNAPs as well as the mitochondrial RNAPs. The robust activity and strict promoter specificity of the phage RNAPs have made them extremely useful as reagents for both in vitro preparation of ...
Rui, Sousa, Srabani, Mukherjee
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Abstract Bacteriophage T7 RNA polymerase (RNAP) is the best characterized member of a widespread family of RNAPs that includes most bacteriophage-encoded RNAPs as well as the mitochondrial RNAPs. The robust activity and strict promoter specificity of the phage RNAPs have made them extremely useful as reagents for both in vitro preparation of ...
Rui, Sousa, Srabani, Mukherjee
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RNA-dependent RNA polymerases in RNA silencing
Biological Chemistry, 2011Abstract RNA-dependent RNA polymerases (RdRPs) synthesize double-stranded RNAs that are processed into small RNAs and mediate gene silencing. Viral RdRPs and cellular RdRPs show little structural homology to each other. Cellular RdRPs play key roles in RNA silencing by producing complementary strands for target RNAs via Dicer-dependent and -
Yoshiko, Maida, Kenkichi, Masutomi
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Picornavirus RNA-dependent RNA polymerase
The International Journal of Biochemistry & Cell Biology, 2009Replication of the picornavirus genome is catalysed by a viral encoded RNA-dependent RNA polymerase, termed 3D polymerase. Together with other viral and host proteins, this enzyme performs its functions in the cytoplasm of host cells. The crystal structure of 3D polymerase from a number of picornaviruses has been determined.
Chee Choy, Kok, Peter C, McMinn
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Ribosomal RNA Synthesis and RNA Polymerase
Nature, 1970MULTIPLE forms of RNA polymerase activity have been isolated from developing sea-urchin embryos, rat liver nuclei and calf thymus1–3. The molecular basis of this heterogeneity is at present unknown but, whatever its basis, the crucial question seems to be whether different enzymes copy different genes.
G P, Tocchini-Valentini, M, Crippa
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Current Opinion in Structural Biology, 2001
The recently determined crystal structure of a bacterial core RNA polymerase (RNAP) provides the first glimpse of this family of evolutionarily conserved cellular RNAPs. Using the structure as a framework, a consistent picture of protein-nucleic acid interactions in transcription complexes has been accumulated from cross-linking experiments.
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The recently determined crystal structure of a bacterial core RNA polymerase (RNAP) provides the first glimpse of this family of evolutionarily conserved cellular RNAPs. Using the structure as a framework, a consistent picture of protein-nucleic acid interactions in transcription complexes has been accumulated from cross-linking experiments.
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Critical Reviews in Biochemistry, 1985
This review will attempt to cover the present information on the multiple forms of eukaryotic DNA-dependent RNA polymerases, both at the structural and functional level. Nuclear RNA polymerases constitute a group of three large multimeric enzymes, each with a different and complex subunit structure and distinct specificity.
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This review will attempt to cover the present information on the multiple forms of eukaryotic DNA-dependent RNA polymerases, both at the structural and functional level. Nuclear RNA polymerases constitute a group of three large multimeric enzymes, each with a different and complex subunit structure and distinct specificity.
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2004
At the end of the 1950s Hoagland and Zamecnik had succeeded in obtaining an in vitro protein synthesis from ribosomes and crude acellular extracts. Ribosomes cannot by themselves achieve a specific protein synthesis and require an information originating in last analysis in the genes.
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At the end of the 1950s Hoagland and Zamecnik had succeeded in obtaining an in vitro protein synthesis from ribosomes and crude acellular extracts. Ribosomes cannot by themselves achieve a specific protein synthesis and require an information originating in last analysis in the genes.
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1973
Publisher Summary This chapter presents the status of RNA polymerases involved in RNA synthesis in mammalian cells, with emphasis on some recent developments in the field of nuclear RNA polymerase. The chapter discusses that the RNA polymerases of eukaryotic nuclei exist in multiple forms. These enzymes are compartmentalized within the nucleus.
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Publisher Summary This chapter presents the status of RNA polymerases involved in RNA synthesis in mammalian cells, with emphasis on some recent developments in the field of nuclear RNA polymerase. The chapter discusses that the RNA polymerases of eukaryotic nuclei exist in multiple forms. These enzymes are compartmentalized within the nucleus.
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RNA polymerase III transcription
Current Opinion in Cell Biology, 1991Remarkable progress has been made in defining the functional significance of the protein-DNA interactions involved in transcription complex formation on yeast tRNA and 5S RNA genes. This new information leads to a re-evaluation of how the class III gene transcription machinery operates.
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RNA Polymerase and the Control of RNA Synthesis
1969Publisher Summary This chapter discusses the mechanism of RNA polymerase action in terms of the regulation of RNA synthesis. The evidence presented indicates that accurate and selective transcription of DNA can be achieved with very pure RNA polymerase.
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