Results 261 to 270 of about 2,226,379 (341)

BEAN and HABAS: Polyphyletic insertions in the DNA-directed RNA polymerase. [PDF]

Protein Sci
Alvarez-Carreño C, Huynh AT, Petrov AS, Orengo C, Williams LD.   +4 more
europepmc   +1 more source

Conversion of Bacillus subtilis RNA polymerase activity in vitro by a protein induced by phage SP01.

, 1975
John J. Duffy, R. Petrusek, E. Peter Geiduschek   +2 more
openalex   +1 more source

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

Advanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang, Zizhang Li, Jingyu Chen, Wenjing Yang, Xingxing He, Peng Wu, Feng Chen, Ziwei Zhou, Chenze Ren, Yuyan Shan, Xiewen Wen, Vassily A. Lyubetsky, Leonid Yu. Rusin, Xiaoshu Chen, Jian‐Rong Yang   +14 more
wiley   +1 more source

T7 RNA polymerase-guided base editor for accelerated continuous evolution in <i>Bacillus subtilis</i>. [PDF]

Synth Syst Biotechnol
Wang B, Wu Y, Lv X, Liu L, Li J, Du G, Chen J, Liu Y.   +7 more
europepmc   +1 more source

One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities

Proceedings of the National Academy of Sciences of the United States of America, 2014
Lorenzo Subissi, C. Posthuma, A. Collet, Jessika C. Zevenhoven-Dobbe, A. Gorbalenya, E. Decroly, E. Snijder, B. Canard, I. Imbert   +8 more
semanticscholar   +1 more source

Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery

Advanced Science, EarlyView.
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou, Xin‐Ge Wang, Xuan‐Ren Shi, Shu‐Ting Sun, Jing Mi, Xiao‐Peng Zhang, Bin‐Cheng Yin, Ying Zhou, Bang‐Ce Ye   +8 more
wiley   +1 more source

Structural basis of RNA polymerase complexes in African swine fever virus. [PDF]

Nat Commun
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H.   +25 more
europepmc   +1 more source

Precise Maps of RNA Polymerase Reveal How Promoters Direct Initiation and Pausing

Science, 2013
Hojoong Kwak, Nicholas J Fuda, Leighton J. Core, J. Lis   +3 more
semanticscholar   +1 more source

Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3‐Regulated HIF1A/HMOX1 Signaling Pathway

Advanced Science, EarlyView.
This study reveals that histone lactylation, a modification derived from lactate, plays a crucial role in ferroptosis resistance in ectopic endometrial stromal cells. This resistance is mediated via the HIF1A/HMOX1 pathway regulated by METTL3. In vivo, a combination of 2‐DG and erastin shows promise as an effective treatment for endometriosis ...
Zongwen Liang, Jinming Liu, Yanling Gou, Honglin Wang, Zhi Li, Yingying Cao, Huiyan Zhang, Ruru Bai, Zongfeng Zhang   +8 more
wiley   +1 more source

Distribution of RNA Polymerase Binding Sites in Fractionated Chromatin

, 1974
Robert T. Simpson
openalex   +1 more source