Results 281 to 290 of about 768,924 (317)

Structural basis of RECQL5-induced RNA polymerase II transcription braking and subsequent reactivation

Zhang L, Gordiyenko Y, Morgan T, Franco C, Vidaković AT, Zhang S.   +5 more
europepmc   +1 more source

Publisher Correction: Promoter-proximal RNA polymerase II termination regulates transcription during human cell type transition. [PDF]

Nat Struct Mol Biol
Lysakovskaia K, Devadas A, Schwalb B, Lidschreiber M, Cramer P.   +4 more
europepmc   +1 more source

Targeting COPA to Enhance Erdafitinib Sensitivity in FGFR‐Altered Bladder Cancer

Advanced Science, EarlyView.
Coatomer protein complex subunit α facilitates the transport of the cargo protein LRPPRC across the Golgi complex and enhances its stability, thereby increasing LRPPRC expression; LRPPRC promotes the stability of ID3 mRNA in an m6A‐dependent manner, thereby decreasing the transcriptional activity of p16 and p21, which leads to increased erdafitinib ...
Huayuan Zhao, Xincheng Gao, Yangkai Jiang, Yanchao Yu, Liang Wang, Jiayin Sun, Miao Wang, Xing Xiong, Chao Huang, Hui Zhang, Guosong Jiang   +10 more
wiley   +1 more source

Transcription elongation of the plant RNA polymerase IV is prone to backtracking. [PDF]

Sci Adv
Fang C, Huang K, Wu X, Zhang H, Gu Z, Wang J, Zhang Y.   +6 more
europepmc   +1 more source

Verteporfin‐Mediated In Situ Nanovaccine Based on Local Conventional‐Dose Hypofractionated Radiotherapy Enhances Antitumor and Immunomodulatory Effect

Advanced Science, EarlyView.
Here gelatinase‐responsive methoxypolyethyleneglycol–PVGLIG–polycaprolactone (mPEG–PVGLIG–PCL) nanoparticles’ loading verteporfin (N@VP) is developed, enhancing radiotherapy via X‐ray‐triggered singlet oxygen generation. Combined with 2 Gy (gray, a radiation dose unit) irradiation, N@VP achieves antitumor efficacy comparable to 8 Gy, and also promotes ...
Zhifan Zhang, Lin Li, Yuchen Ge, Anni Chen, Shanchao Diao, Yueling Yang, Qianyue Chen, Yingling Zhou, Jie Shao, Fanyan Meng, Lixia Yu, Manman Tian, Xiaoping Qian, Zhaoyu Lin, Chen Xie, Baorui Liu, Rutian Li   +16 more
wiley   +1 more source

Comprehensive Analysis of Multi-Omics Data on RNA Polymerase as an Adverse Factor in Head and Neck Squamous Cell Carcinoma. [PDF]

J Inflamm Res
Gu YJ, Zhang J, Liu YJ, Zhang Q, Geng QF.   +4 more
europepmc   +1 more source

Mycobacterial HelD connects RNA polymerase recycling with transcription initiation. [PDF]

Nat Commun
Kovaľ T, Borah N, Sudzinová P, Brezovská B, Šanderová H, Vaňková Hausnerová V, Křenková A, Hubálek M, Trundová M, Adámková K, Dušková J, Schwarz M, Wiedermannová J, Dohnálek J, Krásný L, Kouba T.   +15 more
europepmc   +1 more source

In silico studies to understand the interactions of flavonoid inhibitor with nsp12-RNA dependent RNA polymerase of SARS-CoV-2 and its homologs. [PDF]

Biochem Biophys Rep
Kizhakkiniyakath SA, Choudhury T, Rajan MV, Rathee S, Meena B, Hariprasad G.   +5 more
europepmc   +1 more source

RNA Polymerase II subunits overexpressions induce genome instability and deregulate transcription

Sadurni MM, Jones ML, Pavlou L, Radi M, Kompocholi S, Passaretti P, Gambus A, Gregersen LH, Saponaro M.   +8 more
europepmc   +1 more source

Single-stranded DNA drives σ subunit loading onto mycobacterial RNA polymerase to unlock initiation-competent conformations. [PDF]

Nucleic Acids Res
Vishwakarma RK, Marechal N, Morichaud Z, Blaise M, Margeat E, Brodolin K.   +5 more
europepmc   +1 more source