Results 281 to 290 of about 2,730,472 (338)

A mechanism of synergistic Mediator recruitment in RNA polymerase II transcription activation revealed by single-molecule fluorescence. [PDF]

Mol Cell
Zhou DH, Jeon J, Farheen N, Friedman LJ, Kondev J, Buratowski S, Gelles J.   +6 more
europepmc   +1 more source

Specificity factor of yeast mitochondrial RNA polymerase. Purification and interaction with core RNA polymerase.

, 1987
Alfred H. Schinkel, Marian J.A. Groot Koerkamp, Egbert Touw, Henk F. Tabak   +3 more
openalex   +1 more source

Tailored Xenogeneic‐Free Polymer Surface Promotes Dynamic Migration of Intestinal Stem Cells

Advanced Materials, EarlyView.
This study introduces a PoLymer‐coated Ultra‐stable Surface (PLUS), a nitrogen plasma‐treated poly(ethyleneglycoldimethacrylate), as a stable xenogeneic‐free platform for intestinal stem cell culture. PLUS enhances cell attachment, supports actin‐driven migration, and retains functionality after 3 years of storage. Promoting cytoskeletal reorganization,
Seonghyeon Park, Sang Yu Sun, Jin Gyeong Son, Sun Young Lee, Hyun Kyong Shon, Ohman Kwon, Minseok Lee, Keonwoo Choi, Jemin Yeun, Sung Hyun Yoon, Minkyung Kim, Mi‐Young Son, Tae Geol Lee, Sung Gap Im   +13 more
wiley   +1 more source

Licoflavone B Suppresses Influenza A Virus by Targeting the Viral RNA-Dependent RNA Polymerase (RdRp). [PDF]

Viruses
Fan P, Lv P, Zhang S, Zhu Z, Qian K, Han J, Cui Y, Feng Y, Li Z, Qiang L, Dong Y, Fang T, Jiang T, Yu C, Chi X.   +14 more
europepmc   +1 more source

Identification of New Mediator Subunits in the RNA Polymerase II Holoenzyme from Saccharomyces cerevisiae

, 1998
Claes M. Gustafsson, Lawrence C. Myers, Jenny Béve, Henrik Spåhr, Mary Lui, Hediye Erdjument‐Bromage, Paul Tempst, Roger D. Kornberg   +7 more
openalex   +1 more source

One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities

Proceedings of the National Academy of Sciences of the United States of America, 2014
Lorenzo Subissi, C. Posthuma, A. Collet, Jessika C. Zevenhoven-Dobbe, A. Gorbalenya, E. Decroly, E. Snijder, B. Canard, I. Imbert   +8 more
semanticscholar   +1 more source

Macrophages Mediate Mesoscale Brain Mechanical Homeostasis

Advanced Materials, EarlyView.
We investigated the role of infiltrating immune cells in sculpting the developing brain. Using Brillouin microscopy and active microrheology, we found microglia actively maintain tissue viscoelasticity. Moreover, colony stimulating factor one receptor (CSF1R)‐driven stromal remodeling alters brain mechanics in vivo. These findings link immune activity,
Woong Young So, Bailey Johnson, Patricia B. Gordon, Kevin S. Bishop, Hyeyeon Gong, Hannah A Burr, Jack Rory Staunton, Chenchen Handler, Khanh Loan Ly, Raman Sood, Giuliano Scarcelli, Kandice Tanner   +11 more
wiley   +1 more source

Kinetic characterization of RNA synthesis catalyzed by the model hyperthermophilic archaeon <i>Thermococcus kodakarensis</i> RNA polymerase. [PDF]

mSphere
Cooper Horton SL, Santangelo TJ, Lucius AL, Schneider DA.   +3 more
europepmc   +1 more source

Positioning of σS, the stationary phase σ factor, in Escherichia coli RNA polymerase–promoter open complexes

, 1999
Frédéric Colland, Nobuyuki Fujita, Denise Kotlarz, Jonathan A. Bown, Claude F. Meares, Akira Ishihama, Annie Kolb   +6 more
openalex   +1 more source

Therapeutic Antibodies for Mosquito‐Borne Orthoflavivirus Infections: Discovery, Engineering Approaches, and Advances in mRNA‐Based Delivery Systems

Advanced Therapeutics, EarlyView.
This review explores how antibody engineering and display technologies are driving therapeutic advances against mosquito‐borne orthoflaviviruses such as Zika, dengue, and yellow fever viruses. It highlights diverse neutralizing targets on the envelope protein, including the conserved fusion loop, and discusses how Fc engineering, rational antigen ...
Ana Clara Barbosa Antonelli, Lucas Silva Rodrigues, Maria Clara Moura Pinheiro, Sylvia Barbosa Pinhate, Marcelo de Macedo Brígido, Andréa Queiroz Maranhão   +5 more
wiley   +1 more source